Epidermal Graft Accelerates the Healing of Acute Wound: A Self-controlled Case Report

Bystrzonowski, Nicola; Hachach‐Haram, Nadine; Kanapathy, Muholan; Richards, Toby; Mosahebi, Afshin

doi:10.1097/gox.0000000000001119

Cited by 4 publications

(3 citation statements)

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“…In addition, besides the lower donor site morbidity, the donor site healing time of EG is also significantly shorter compared with SSG. The rapid healing and aesthetically superior outcome of the EG donor site is because of the superficial nature of the harvested skin and the design of the harvester, which harvests 128 small islands of EG (micrographs) with a 2 mm gap . This enables keratinocytes and melanocytes to proliferate and migrate from the healthy surrounding skin to heal the donor site in a rapid manner.…”

Section: Discussionmentioning

confidence: 99%

“…Prior to grafting, the wound was cleaned using wound irrigation solution and debrided if necessary. The suction head of the CelluTome Epidermal Harvesting System was applied to the donor site (thigh) for 30 to 40 minutes to harvest EG as per protocol . The harvested EG was then transferred onto the wound using a non‐adhering silicone dressing (Adaptic Touch, Systagenix, Gatwick, UK).…”

Section: Methodsmentioning

confidence: 99%

“…An emerging option of autologous skin grafting that has the potential to overcome the challenges of donor site morbidity is epidermal graft (EG). EG involves harvesting only the epidermal layer of the skin from the donor site by applying continuous negative pressure on normal skin to raise blisters . The roof of the blister, which is the epidermis, is then excised and transferred onto the wound.…”

Section: Introductionmentioning

confidence: 99%

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Comparative study on the donor site aesthetic outcome between epidermal graft and split‐thickness skin graft

Kanapathy

Mosahebi

2018

International Wound Journal

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Donor site aesthetic outcomes of epidermal graft (EG) vs split‐thickness skin graft (SSG) have yet to be objectively compared. Here, we evaluate donor site healing using a validated scar assessment tool and digital colorimetric technique, which compares colour in a consistent and objective manner. Ten patients (SSG (n = 5) and EG (n = 5)) were included. Donor site scarring was evaluated using the Vancouver Scar Scale (VSS) at Week 6 and Month 3. Colorimetric measurement was performed at Weeks 3 and 6 and Month 3. The mean donor site healing time for EG was significantly shorter (EG: 4.6 days (95% c.i. 3.8‐5.3), SSG: 16.8 days (95% c.i. 13.3‐20.1) (P = 0.003)). The VSS scores of the EG donor site were lower at Week 6 and Month 3(P < 0.001). The colour match between the donor site and surrounding skin for EG was better compared with SSG at all time points and was almost identical to their surrounding healthy skin at Month 3. This study is the first to objectively measure the clinical appearance of the EG donor site against SSG. EG donor site has faster healing with excellent scarring and good colour match with its surrounding normal skin at all time points compared with SSG.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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