Epidermoid carcinoma arising in a pilonidal sinus

Squamous‐Cell Carcinoma Arising in a Pilonidal Sinus: A Case Report and Review of the Literature

“…The estimated incidence of carcinoma in pilonidal disease is 0.1%, 11,14 although no cases were reported in 86,333 servicemen treated for pilonidal disease during World War II, 10 probably due to earlier definitive excisions of the benign lesions.…”

“…The role of chronic irritation as an etiologic factor for squamous‐cell carcinoma is well known. Cases of such a tumor arising in draining fistulas, sinuses, and scars have been reported in chronic osteomyelitis, 1,2 pleural empyema, 3 suppurative hydradenitis, 4–6 and pilonidal sinus, 7–19 as well as old scars, 20,21 especially burn scars, the well‐known Marjolin ulcer 22–25 …”

Basal Cell Epithelioma Arising in a Pilonidal Sinus

“…Weinstein et al14 summarized the suspicious signs of malignancy: "(1) long standing and persist¬ ent pilonidal sinuses with drainage, (2) sud¬ den rapid growth, (3) overgrowth above the skin level, (4) friability, (5) ulcération, (6) hemorrhage in the tissues, (7) external bleeding, (8) and most commonly, bleeding in the sinuses which have been present for many years. There has been an increasing number of reports since 1956 when Hall et al13 described the first case in American literature.…”

Eight Patients With Pilonidal Carcinoma in One Decade—Is the Incidence Rising?

“…Fewer than 130 cases were reported in the literature so far [1]. Although the calculated incidence varies between publications, it is estimated that malignant transformation occurs in about 0.1% of patients with the pilonidal disease [2,3].…”