Epidural anaesthesia with bupivacaine does not cause increased oedema in small gut anatomoses in pigs

Abstract

Surgery did not increase gut wall water content, but acute oedema formation resulted in the peri-resectional mesenterial tissue, more prominently so in the bupivacaine group.

Consensus Review of Optimal Perioperative Care in Colorectal Surgery

“…114,120,121 Perfusion of the splanchnic area after establishment of the epidural block is probably more closely associated with changes in mean arterial pressure than with changes in cardiac output. 122 Therefore, vasopressors to maintain pressure should be considered.…”