Epidural Analgesia for Labor and Delivery in a Patient with Von Willebrandʼs Disease

Cohen, Sidney; Daitch, Jonathan S.; Amar, David; Goldiner, Paul L.

doi:10.1097/00132582-198910000-00068

Cited by 19 publications

(30 citation statements)

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“…Several case reports have shown women with VWD received epidural anaesthesia without bleeding complications [61,[75][76][77]. In a series, eight women with VWD received regional anaesthesia during labour and delivery without bleeding complications and only one woman received prophylactic therapy as the clotting factor levels were >50 IU dL )1 in the other cases [54].…”

Section: Von Willebrand's Diseasementioning

confidence: 99%

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

et al. 2006

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Summary. The gynaecological and obstetric management of women with inherited coagulation disorders requires close collaboration between obstetrician/ gynaecologists and haematologists. Ideally these women should be managed in a joint disciplinary clinic where expertise and facilities are available to provide comprehensive assessment of the bleeding disorder and a combined plan of management. The haematologist should arrange and interpret laboratory tests and make provision for appropriate replacement therapy. These guidelines have been provided for healthcare professionals for information and guidance and it is also intended that they are readily available for women with bleeding disorders.

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Section: Von Willebrand's Diseasementioning

confidence: 99%

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

et al. 2006

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“…Three cases of Cesarean section were conducted uneventfully in patients with VWD, using epidural anesthesia [3,4]. Because VWF increases three-to fi vefold over baseline in pregnant women in their fi nal trimester, neuraxial block would be feasible for parturients who have mild VWD, without any treatment.…”

Section: Discussionmentioning

confidence: 99%

Considerations for epidural anesthesia in a patient with type 1 von Willebrand disease

2009

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Epidural anesthesia, combined with general anesthesia, was performed in a patient with type 1 von Willebrand disease (VWD). VWD is a common inherited bleeding disorder, and an anesthetic concern in patients with VWD is susceptibility to postoperative bleeding and epidural or spinal hematoma associated with neuraxial block. After confirming the patient's responsiveness to 1-desamino-8-D-arginine vasopressin (DDAVP) and obtaining informed consent, epidural anesthesia was performed to avoid the use of analgesics that inhibit platelet function. The patient's postoperative course was uneventful. Epidural anesthesia could be one of the choices of treatment for postoperative pain in those patients with type 1 VWD for whom the conditions discussed are fulfilled, to ensure safe usage of this technique.

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“…Neuraxial interventions are contraindicated in patients with vWD whose bleeding disorders are not healed. Although vWD is quite common among bleeding disorders, there are very few case reports describing an anesthetic method for vWD patients (Hara et at., 2009;Caliezi et al, 1998;Jones et al, 1999;Milaskiewicz et al, 1990;Cohen et al, 1989). Paucity of large case series showing that epidural interventions are safe makes anesthetists hesitate when conducting anesthesia on women with vWD.…”

Section: Von Willebrand Disease (Vwd)mentioning

confidence: 99%

Contraindications - Hemorrhage and Coagulopathy, and Patient Refusal

Çekiç¹,

Beşir²

2012

Epidural Analgesia - Current Views and Approaches

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Epidural Analgesia for Labor and Delivery in a Patient with Von Willebrandʼs Disease

Cited by 19 publications

References 0 publications

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization

Considerations for epidural anesthesia in a patient with type 1 von Willebrand disease

Contraindications - Hemorrhage and Coagulopathy, and Patient Refusal

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