Epidural analgesia for labour in a parturient with neurofibromatosis

Labor analgesia and cesarean section in women affected by tuberous sclerosis: report of two cases

“…in neurofibromatosis or TS), it should first be excluded by MRI before administering any type of neuraxial block. 23 Others lesions may interfere with anesthetic management of patients with TS. Oral tubers have been described in up to 15% of patients with TS.…”

A parturient with neurofibromatosis type 2: anesthetic and obstetric considerations for delivery

“…In NF1, where 5-10% of cases also have CNS tumor involvement, the conduct of neuraxial anesthesia still requires special attention. Dounas et al 11 described the first case of successful epidural analgesia for labor in a 26-year-old woman with von Recklinghausen's disease (NF1), after they confirmed negative involvement of spinal cord neurofibromas by clinical examination and CT scan. Sahin and Aypar 12 also reported successful spinal anesthesia in a male patient with NF1 after CNS tumor involvement was ruled out.…”

Correction of intraoperative coagulopathy in a patient with neurofibromatosis type I with intravenous desmopressin (DDAVP)

“…Recommendations for lumbar and cranial imaging in patients with NF1 have been made to ensure the safety of neuraxial anesthesia both from the point of view of intracranial hypertension and of paraspinal tumors. [5][6][7] The choice of spinal anesthesia in our case required consideration of a lumbar tumor and prompted investigation by MRI. While computerized tomography (CT) scanning for similar purposes has been described and considered safe for the term pregnancy, MRI is preferred.…”