Epigenetic Discrimination of Lebanese Monozygotic Twins as a Promising Forensic Approach

Romanos, Paula; Borjac, Jamilah

doi:10.1134/s1022795421010129

Cited by 2 publications

(1 citation statement)

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“…Our first study showed that the use of rapidly mutating (RM) Y -STRs recently introduced in the forensic casework did not improve distinction among the male Lebanese MZs pairs (Romanos & Borjac, 2018). However, our second study showed that 71.42% of both male and female Lebanese MZs pairs were epigenetically discriminated despite the fact that individuals within the same MZ pair has the same genetic composition thus they share the same DNA profile (Romanos & Borjac, 2020). The use of epigenetics biomarkers, Alu-Sp & Alu-E2F3 located…”

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confidence: 81%

Epigenetic Status of Lebanese Dizygotic Twins

Romanos

Borjac

2021

GABJ

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Lebanon is an eastern Mediterranean country with a small population of only 4 million (Abbas et al. 2020). It is characterized for its distinct human genetic, cultural, ethnic, and religious diversity (Haber et al. 2011). The average live twinning births rate in Lebanon is 18.9/1000 (Romanos & Borjac, 2018). Twins can be either monozygotic (MZ) or dizygotic (DZ). The difference between them is how they are formed during embryogenesis (Hoekstra et al. 2008). When a single sperm fertilizes a single egg, it splits then in two genetically identical twins (Xu et al. 2015). However, in fraternal twins case, separate eggs are fertilized by separate sperm to yield genetically different twins (Martino et al. 2013).

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confidence: 81%