Epigenetic profiling of prostate cancer reveals potential prognostic signatures
Simon Bernatz,
Ian G. Reddin,
Tim R. Fenton
et al.
Abstract:Purpose
While epigenetic profiling discovered biomarkers in several tumor entities, its application in prostate cancer is still limited. We explored DNA methylation-based deconvolution of benign and malignant prostate tissue for biomarker discovery and the potential of radiomics as a non-invasive surrogate.
Methods
We retrospectively included 30 patients (63 [58–79] years) with prostate cancer (PCa) who had a multiparametric MRI of the prostate bef… Show more
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