Epigenetics and phenotypic variability: some interesting insights from birds

Frésard, Laure; Morisson, Mireille; Brun, Jean- Michel J.- . M.; Collin, Anne; Pain, Bertrand; Minvielle, Francis; Pitel, Frédérique

doi:10.1186/1297-9686-45-16

Cited by 75 publications

(59 citation statements)

References 164 publications

(168 reference statements)

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“…Adaptive phenotypic plasticity may, however, involve modification of the epigenotype without change of the genomic structure of the organism, which may cause the neural, hormonal and/or enzymatic changes needed (Crews 2010, Nelson & Monteggia 2011. Epigenetic effects have been shown to be involved in the differentiation of cell lines and trigger altered gene ex pression (Jablonka & Raz 2009), and they can be induced by environmental temperature and contribute to adaptations to novel environments and be a source of phenotypic variation in ecological traits of fishes (Morán & Pérez-Figueroa 2011, Jonsson & Jonsson 2014) and other vertebrates (Frésard et al 2013, Burton & Metcalfe 2014, Varriale 2014.…”

Section: Discussionmentioning

confidence: 99%

Linking embryonic temperature with adult reproductive investment in Atlantic salmon Salmo salar

Jönsson¹,

Jönsson²,

Finstad³

2014

Mar. Ecol. Prog. Ser.

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The expression of fitness-related traits, such as egg and gonad size, often varies among habitats and exhibits clinal variation along climatic and latitudinal gradients. However, the mechanisms allowing such variations are obscure and have been ascribed to both phenotypic plasticity and genetic adaptation. We experimentally tested whether variation in egg and gonad size of a poikilotherm vertebrate is influenced by the temperature individuals experienced during embryogenesis, possibly as an epigenetic effect. Atlantic salmon Salmo salar eggs were incubated under 3 embryonic thermal regimes: cold, mixed and warm treatments. The cold group received ambient river water (mean ± SD: 2.6 ± 0.4°C) and the warm group received water at 4.6°C above ambient temperature, the expected temperature in the river towards the end of this century, from fertilization until exogenous feeding commenced. The mixed group received ambient river water until hatching, whereupon the larvae received heated water until exogenous feeding commenced. When exogenous feeding was initiated, all fish were reared under identical, natural thermal conditions. At adulthood, fish that developed from warm-incubated eggs were largest, had the highest mass−length relationship and developed larger eggs and higher gonad mass relative to their own body size. There was no similar effect of thermal environment during larval development. The treatment did not affect age of maturity or fecundity. Thus, thermal conditions during embryogenesis affected the expression of adult life-history traits, a mechanism by which fish may rapidly change the size of their propagules to the anticipated thermal offspring environment. This is a novel result explaining variation in these core life-history traits.

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Section: Discussionmentioning

confidence: 99%

Linking embryonic temperature with adult reproductive investment in Atlantic salmon Salmo salar

Jönsson¹,

Jönsson²,

Finstad³

2014

Mar. Ecol. Prog. Ser.

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“…Exposure to specifi c fl avors or odors can also modulate the olfactory system and taste preference in the offspring (Schaal et al 2000 ;Ong and Muhlhausler 2011 ;Todrank et al 2011 ). In certain bird species, females can load antibodies against encountered pathogens into the eggs' yolk, providing protection to their progeny (Frésard et al 2013 ). (3) Peri-and postnatally, the amount and quality of maternal care strongly infl uence the offspring's behavior in adulthood.…”

Section: Appendix 1: Experimental Methods To Examine Different Routesmentioning

confidence: 99%

Epigenetic Risk Factors for Diseases: A Transgenerational Perspective

Bohacek

Mansuy

2016

Epigenetics and Neuroendocrinology

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Each individual is determined by a combination of genetic and non-genetic factors that together shape physiological and biological functions during development and adulthood. While genetic features are embedded in the DNA sequence inherited from parents, non-genetic features (which include epigenetic modifi cations) are acquired through experiences and environmental exposure across life. However, it is now acknowledged that non-genetic features can also be inherited from parents and propagate across generations. This chapter discusses the concept of non-genetic germline inheritance in mammals and examines possible routes of transmission of non-genetic information involving germline-dependent and germline-independent modes of transfer. It reviews current evidence that environmental factors can induce non-genetic alterations in the germline that can impact behavioral and physiological features in the offspring. This chapter also addresses the underlying molecular mechanisms, provides initial insight into the implication of epigenetic marks and noncoding RNAs in male germ cells, and questions the way non-genetic modifi cations can be induced and maintained in germ cells. It highlights promising areas of current research and refl ects on evolutionary perspectives and future challenges.

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“…Relevant researches on poultry epigenetics (Berghof, Parmentier, & Lammers, ; Feeney, Nilsson, & Skinner, ; Frésard et al., ; Gao et al., ; Leurox et al., ; Li, Guo, Zhang, Gao, & Guo, ; Li et al., ) revealed that epigenetic modifications may occur from the first stage of egg, when the mother provides an environmental signature through the egg content (Frésard et al., ). However, studies approaching the transgenerational epigenetic variance estimation (Jablonka, ; Jablonka & Raz, ; Lopes, Bastiaansen, Janss, Knol, & Bovenhuis, ; Varona et al., ) for economically important traits are still scarce in the literature.…”

Section: Introductionmentioning

confidence: 99%

Transgenerational epigenetic variance for body weight in meat quails

Paiva

Resende

et al. 2018

J Animal Breeding Genetics

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We aimed to estimate transgenerational epigenetic variance for body weight using genealogical and phenotypic information in meat quails. Animals were individually weighted from 1 week after hatching, with weight records at 7, 14, 21, 28, 35 and 42 days of age (BW7, BW14, BW21, BW28, BW35 and BW42, respectively). Single-trait genetic analyses were performed using mixed models with random epigenetic effects. Variance components were estimated by the restricted maximum likelihood method. A grid search for values of autorecursive parameter (λ) ranging from 0 to 0.5 was used in the variance component estimation. This parameter is directly related to the reset coefficient (ν) and the epigenetic coefficient of transmissibility (1-ν). The epigenetic effect was only significant for BW7. Direct heritability estimates for body weight ranged in magnitude (from 0.15 to 0.26), with the highest estimate for BW7. Epigenetic heritability was 0.10 for BW7, and close to zero for the other body weights. The inclusion of the epigenetic effect in the model helped to explain the residual and non-Mendelian variability of initial body weight in meat quails.

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Epigenetics and phenotypic variability: some interesting insights from birds

Cited by 75 publications

References 164 publications

Linking embryonic temperature with adult reproductive investment in Atlantic salmon Salmo salar

Linking embryonic temperature with adult reproductive investment in Atlantic salmon Salmo salar

Epigenetic Risk Factors for Diseases: A Transgenerational Perspective

Transgenerational epigenetic variance for body weight in meat quails

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