Epikeratophakia for the Treatment of Keratoconus

Kaufman, Herbert E.; Werblin, Theodore P.

doi:10.1016/0002-9394(82)90537-2

Cited by 118 publications

(21 citation statements)

References 7 publications

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“…Epikeratophakia, a form of onlay lamellar keratoplasty, for the treatment of keratoconus was first introduced by Kaufmann and Werblin in 1982 [2]. The technique employs non-refractive, acellular, freeze-dried stromal lenticules prepared from donor corneas.…”

Section: Introductionmentioning

confidence: 99%

Long-term functional and topographic results seven years after epikeratophakia for keratoconus

Spitznas

Eckert

Frising

et al. 2002

Graefe's Arch Clin Exp Ophthalmol

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EKP was able to render PKP unnecessary in 32 of 36 eyes during the entire observation period. It was successful in permanently flattening the ectatic cornea and reducing astigmatism while restoring a symmetrical and smooth corneal surface. As a result, visual acuity improved considerably. In view of the young age of keratoconus patients needing surgery, and the fact that the lifetime of full-thickness corneal grafts is limited, EKP should be considered a valuable alternative to PKP in contact-lens-intolerant cases of keratoconus without central scarring.

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Section: Introductionmentioning

confidence: 99%

Long-term functional and topographic results seven years after epikeratophakia for keratoconus

Spitznas

Eckert

Frising

et al. 2002

Graefe's Arch Clin Exp Ophthalmol

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“…Following posterior dissection of the conjunctiva and removal of host epithelium, a donor corneoscleral lenticule devoid of endothelium and Descemet's membrane is placed over the host cornea and sutured over it at the periphery to sclera. 9 Epikeratoplasty was first described by Kaufman and Werblin 46 in treatment of aphakia, myopia, and keratoconus in children. It is considered a safe and easy procedure, especially in eyes with thinned corneas making extensive host corneal manipulation risky.…”

Section: Treatmentmentioning

confidence: 99%

Keratoglobus

Wallang

Das²

2013

Eye

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Keratoglobus is a rare noninflammatory corneal thinning disorder characterised by generalised thinning and globular protrusion of the cornea. It was first described as a separate clinical entity by Verrey in 1947. Both congenital and acquired forms have been shown to occur, and may be associated with various other ocular and systemic syndromes including the connective tissue disorders. Similarities have been found with other noninflammatory thinning disorders like keratoconus that has given rise to hypotheses about the aetiopathogenesis. However, the exact genetics and pathogenesis are still unclear. Clinical presentation is characterised by progressive diminution resulting from irregular corneal topography with increased corneal fragility due to extreme thinning. Conservative and surgical management for visual rehabilitation and improved tectonic stability have been described, but remains challenging. In the absence of a definitive standard procedure for management of this disorder, various surgical procedures have been attempted in order to overcome the difficulties. This article reviews the aetiological factors, differential diagnosis, histopathology, and management options of keratoglobus.

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“…The improved corneal curvature (!50.0 D) was obtained by the flattening effect of the sutures, which were placed as in other lamellar techniques, such as epikeratophakia in keratoconus patients. 19 In our series, visual acuity improved after surgery. The final visual results were satisfying and similar to those achieved with PKP 20,21 and other lamellar keratoplasty techniques.…”

Section: Discussionmentioning

confidence: 84%