2018
DOI: 10.3390/brainsci8020022
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Epilepsy: A Call for Help

Abstract: Epilepsy is a considerable individual and social economic burden. In properly selected patients, epilepsy surgery can provide significant relief from disease, including remission. However, the surgical treatment of epilepsy lags in terms of knowledge and technology. The problem arises due to its slow adaptation and dissemination. This article explores this issue of a wide treatment gap and its causes. It develops a framework for a rational decision-making process that is appropriate for extant circumstances an… Show more

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Cited by 2 publications
(3 citation statements)
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“…Epilepsy is a global concern, with a high societal cost that is concentrated in the approximately one in three patients who have uncontrolled seizures despite adequate trials of anti-seizure medications 6–8. Access to surgical therapy, which offers up to a 50%–80% rate of freedom from disabling seizures for patients with focal-onset DRE, features particularly tight EMU bottlenecks that can result in major diagnostic and subsequent treatment delays 4 7 9 10. In one study that compared two epilepsy centres in Canada and Mexico, the average wait time from first epilepsy consult to videoelectroencephalographic (EEG) was reported as 15.1 months and 27.4 months in Canadian and Mexican centres, respectively 11.…”
Section: Ethics Challenges Unique To Epilepsy Monitoring Unitsmentioning
confidence: 99%
See 1 more Smart Citation
“…Epilepsy is a global concern, with a high societal cost that is concentrated in the approximately one in three patients who have uncontrolled seizures despite adequate trials of anti-seizure medications 6–8. Access to surgical therapy, which offers up to a 50%–80% rate of freedom from disabling seizures for patients with focal-onset DRE, features particularly tight EMU bottlenecks that can result in major diagnostic and subsequent treatment delays 4 7 9 10. In one study that compared two epilepsy centres in Canada and Mexico, the average wait time from first epilepsy consult to videoelectroencephalographic (EEG) was reported as 15.1 months and 27.4 months in Canadian and Mexican centres, respectively 11.…”
Section: Ethics Challenges Unique To Epilepsy Monitoring Unitsmentioning
confidence: 99%
“…Guidance on best practices serves to eliminate bias and increase trust in the delivery of healthcare in both routine and challenging circumstances 1. The management of patients with epilepsy represents a major pressure on resource allocation in healthcare and could benefit significantly from a tightening of care processes 2–5. Indeed, the epilepsy literature increasingly advocates for early referral of patients with drug-resistant epilepsy (DRE) to dedicated epilepsy centres for resource-intensive, continous video-EEG monitoring and potential life-saving surgical intervention.…”
Section: Introductionmentioning
confidence: 99%
“…Epilepsy is a chronic neurological disorder characterized by recurrent seizures due to abnormal brain electrical activity in [35,13]. The exact cause of these seizures remains unclear, but an imbalance between excitation and inhibition plays a central role [52,43]. AEDs are the mainstay of treatment for epilepsy, aiming to modulate neuronal excitability.…”
mentioning
confidence: 99%