Epilepsy and associated psychopathology in young people with intellectual disability

Lewis, Joan; Tonge, Bruce John; Mowat, David; Einfeld, Stewart; Siddons, Heather Michelle; Rees, Vaughan W.

doi:10.1046/j.1440-1754.2000.00487.x

Cited by 43 publications

(28 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is considered to reflect some underlying organic cause associated with more severe levels of intellectual disability (Lewis et al, 2000;Murphy et al, 1998).…”

mentioning

confidence: 99%

Impact of Additional Disabilities on Adaptive Behavior and Support Profiles for People With Intellectual Disabilities

Harries

Guscia

Nettelbeck

et al. 2009

American Journal on Intellectual and Developmental Disabilities

View full text Add to dashboard Cite

Numerous researchers have reported a high incidence of additional disabilities coexisting with intellectual disabilities. Although an intuitive link can be made between the existence of multiple disabilities and greater need for support, little has been reported about this relationship. Using measures of adaptive functioning and support needs, we examined the extent to which adaptive and challenging behaviors and consequent support needs (including medical) were impacted by the presence and severity of additional disabilities for individuals with intellectual disabilities. Results show that adaptive behaviors and support needs were meaningfully related to the number and severity of additional disabilities present, whereas this was not so for challenging behaviors. Findings are discussed in terms of contemporary models of disability and functioning.

show abstract

“…This is considered to reflect some underlying organic cause associated with more severe levels of intellectual disability (Lewis et al, 2000;Murphy et al, 1998).…”

mentioning

confidence: 99%

Impact of Additional Disabilities on Adaptive Behavior and Support Profiles for People With Intellectual Disabilities

Harries

Guscia

Nettelbeck

et al. 2009

American Journal on Intellectual and Developmental Disabilities

View full text Add to dashboard Cite

show abstract

“…Lewis et al (2000) studied children with low IQ to determine whether those who also had epilepsy were doing worse. Although results did not reach statistical significance, children who had active epilepsy had the highest total behavior problem scores (Lewis et al 2000). In a study by Sabaz et al (2001), 65% of the children with both low IQ and epilepsy scored in the clinically abnormal range compared with 41% of those with mental retardation alone.…”

mentioning

confidence: 99%

Behavior and mental health problems in children with epilepsy and low IQ

Buelow

Austin

Perkins

et al. 2003

Dev Med Child Neurol

View full text Add to dashboard Cite

The purpose of this cross-sectional descriptive study was to describe the particular types of behavioral problems, self-concept, and symptoms of depression experienced by children with both low IQ and epilepsy. Three groups of children (83 males, 81 females; mean age 11 years 10 months, SD 1 year 10 months; age range 9 to 14 years) with epilepsy were compared: (Group 1) Low IQ (<85), n=48, 25 males, 23 females; (Group 2) Middle IQ (85 to 100), n=58, 24 males, 34 females; and (Group 3) High IQ (>100), n=58, 34 males, 24 females. The Child Behavior Checklist, Piers-Harris SelfConcept Scale, and Children's Depression Inventory were used to measure behavior, self-concept, and depression respectively. Results indicated that children in the Low IQ group had the most behavioral and mental health problems. Additionally, there were IQ group-by-sex interactions, with females in the Low IQ group being at the highest risk for poor self-concept. Findings suggest that children with both epilepsy and low IQ should be carefully assessed for mental health problems in the clinical setting.Children with chronic epilepsy and children with a low IQ have each been shown to be at increased risk for quality of life problems. Research studies focusing on children with epilepsy and normal IQ, or on children with mental retardation * who do not have epilepsy, show that mental retardation and epilepsy are each independently related to poor quality of life and psychosocial problems (Austin et al. 1994(Austin et al. ,1996Lewis et al. 2000;Sabaz et al. 2001). Because each disorder is associated with such problems it is probable that children with both disorders will experience even greater problems than those with just one of the disorders. Among children with epilepsy, 28 to 38% have some degree of mental retardation (Steffenburg et al. 1996). In addition, there is an unexpectedly high number of children with both epilepsy and low IQ (70 *Correspondence to second author at 1111 Middle Drive, NU 492, Indiana University School of Nursing, Indianapolis, Indiana 46202-5107, USA., joausti@iupui.edu. * UK usage: learning disability. NIH Public Access NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript to 80) who do not fit the DSM-IV (American Psychiatric Association 1994) criteria for mental retardation (Dodson 2001). On average, the IQ in children with epilepsy is 10 points lower than that of their healthy, age-matched peers (Dodson 2001). Despite the strong relationship between epilepsy and low IQ, only a few studies have addressed the psychosocial and mental health problems of this population.Epidemiological studies of children with mental retardation and epilepsy have established that there are high rates of psychopathology. Rates of psychiatric disorders range from 50 to 59% in children with both epilepsy and mental retardation (Rutter 1989, Steffenburg et al. 1996. The most common psychiatric issues include psychoses, depression attention-deficithyperactivity disorder, socialization problems, aberrant behavior...

show abstract

“…Goulden et al (18) documented prevalence of mental retardation of pre‐ or perinatal etiology in 28 to 38% of children with epilepsy. Despite this high prevalence rate, minimal research has specifically addressed the impact of epilepsy with coexisting ID on HRQOL in children (19,20). This research has shown conflicting results due to differences in control groups, psychosocial instruments used, and methodologic problems in classification of epilepsy syndrome and evaluation of seizure severity.…”

mentioning

confidence: 99%

The Health‐Related Quality of Life of Children with Refractory Epilepsy: A Comparison of Those With and Without Intellectual Disability

et al. 2001

View full text Add to dashboard Cite

Summary:Purpose: To determine whether refractory epilepsy affects the health-related quality of life (HRQOL) of children with or without intellectual disability (ID), and if the presence of ID independently compromises HRQOL in children with refractory epilepsy.Methods: Subjects were parents of children with refractory epilepsy, whose syndrome had been defined using ILAE (International League Against Epilepsy) criteria and video-EEG monitoring. Children had the presence or absence of ID determined by formal neuropsychological or educational assessment. The relative effect of epilepsy on the two intellectual ability groups was determined using relevant clinical variables. Parents completed a valid epilepsy-specific HRQOL questionnaire for children, the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE), and, depending on intellectual ability level, the Child Behaviour Checklist or Developmental Behaviour Checklist.Results: Both intellectually normal children with epilepsy and children with epilepsy and ID were more likely to have psychosocial problems compared with their respective intellectual ability reference populations. The results also revealed that children with ID had reduced HRQOL compared with intellectually normal children; a result independent of epilepsy. Analysis of the relationship between epilepsy variables and HRQOL revealed that the QOLCE was the most sensitive in detecting variation in age at onset, seizure frequency, and medications taken. Conclusions:The HRQOL of children with refractory epilepsy is greatly affected, regardless of intellectual ability level. The presence of ID in children with epilepsy independently depresses HRQOL outcomes. Compared with two generic HRQOL measures, the QOLCE was the most sensitive measure to variation in epilepsy variables.

show abstract

Epilepsy and associated psychopathology in young people with intellectual disability

Abstract: The results suggest that epilepsy has little or no influence on problem behaviours for young people with ID. Our attempt to understand the pathogenesis of behaviour problems in persons with ID may be better directed towards understanding genetic mechanisms than epilepsy pathologies.

Cited by 43 publications

References 13 publications

Impact of Additional Disabilities on Adaptive Behavior and Support Profiles for People With Intellectual Disabilities

Impact of Additional Disabilities on Adaptive Behavior and Support Profiles for People With Intellectual Disabilities

Behavior and mental health problems in children with epilepsy and low IQ

The Health‐Related Quality of Life of Children with Refractory Epilepsy: A Comparison of Those With and Without Intellectual Disability

Contact Info

Product

Resources

About