Epilepsy in the families of epileptics

Eisner, Víctor; Pauli, Lydia L.; Livingston, Samuel

doi:10.1016/s0022-3476(60)80186-2

Cited by 16 publications

(5 citation statements)

References 8 publications

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“…Both observations probably suggest that patients with monogenic recessive disorders do not constitute a big proportion of epilepsy patients as compared to those with multifactorial aetiology. This has been observed world-wide as monogenic primary epilepsies are rare accounting for less than 1% of total cases [14][15][16][17] . The majority of genetically influenced epilepsy is multifactorial where the family history reflect on the familial aggregation.…”

Section: Discussionmentioning

confidence: 98%

“…These include head injury 6,7 , perinatal insults 8,9 , central nervous system (CNS) infections 10,11 and febrile convulsions 12,13 . The contribution of genetic factors to the aetiology of epilepsy is by now well recognised [14][15][16][17] . Consanguinity, which is widely practised in Jordan, lead to an increase in the incidence of mono-genic recessive disorders including epilepsy [18][19][20] .…”

Section: Introductionmentioning

confidence: 99%

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Risk factors for childhood epilepsy: a case-control study from Irbid, Jordan

Daoud

Batieha

Bashtawi

et al. 2003

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Positive family history for epilepsy, head trauma, febrile convulsions and abnormal perinatal history were shown to have a statistically significant association with epilepsy in patients attending Princess Rahma Teaching Hospital in Northern Jordan. Although consanguinity is widely practised in Jordan, it appears that it does not increase the risk of epilepsy probably due to the small contribution of monogenic recessive epilepsies to the population with epilepsy.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Risk factors for childhood epilepsy: a case-control study from Irbid, Jordan

Daoud

Batieha

Bashtawi

et al. 2003

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“…In a study of epilepsy incidence in Ethiopia, 22% of those with epilepsy had a family history of epilepsy 31 . In another study, it was stated that the children who had major motor epilepsy in their families had an increased chance of developing epilepsy 15 . In a Turkish study 26 there was at least one epilepsy incidence among the close relatives of 27% of the cases 26 .…”

Section: Discussionmentioning

confidence: 99%

“…Thus, preva-lence investigations are conducted cross-sectionally in smaller populations than necessary for the studies of incidence, and such investigations are preferable in developing countries 1 . According to the results of previous studies, epilepsy prevalence is closely related to multiple variables such as age, region, gender, heredity, disease histories in childhood, traffic accidents, trauma and intoxication, vascular diseases like arterio-venous malformations and aneurysms, tumours, degenerative neurological disorders and toxic causes, like alcohol [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] . The present study aimed to determine the relationship between epilepsy prevalence and its risk factors in Kucukcekmece, an intermediate rural to urban settlement in Istanbul.…”

Section: Introductionmentioning

confidence: 99%

Epilepsy prevalence in a rural area in Istanbul

Önal

Tümerdem

Öztürk

et al. 2002

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This study is a field study with cross-section and case control conducted in the Kucukcekmece Region of Istanbul between June 1999 and February 2000. Four hundred and ninety three dwellings selected by a simple random sampling method were visited. From a population of 2187, 58 people, after filling in a questionnaire were suspected to have epilepsy. Following an interview, neurological examination and an electroencephalogram (EEG) 17 were diagnosed as having epilepsy. Lifetime epilepsy prevalence was 0.8%. 41.2% of the 17 epilepsy cases had partial epilepsy ( n= 7), 47.0% had generalized (n = 8) and in 11.8% seizures could not be classified ( n= 2). The risk factors for epilepsy in the control group ( n= 125) from the same region and those with epilepsy were investigated by means of logistic regression analyses. Educational status (odds ratio : 1.82, 95% confidence interval : 1.13-2.94; P= 0.01), profession (OR : 0.76, 95% CI : 0.60-0.97; P= 0.03), history of epilepsy in the family (OR : 0.67, 95% CI : 0.47-0.94; P= 0.02) were determined to be correlated with epilepsy. The results have drawn attention to the fact that individuals should be informed about epilepsy.

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“…The knowledge of dermatoglyphic pattern of a typical epileptic with the above finger print pattern can hope to have a better quality of life by taking precautions and avoid epileptic trigger factors in genetically predisposed individuals. 4,5…”

Section: Discussionmentioning

confidence: 99%

Study of Dermatoglyphic Patterns of Digits in Patients with Primary Generalized Epilepsy

Kumar¹,

Suresh²,

Asha³

et al. 2015

Medico-Legal Update

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The pattern of papillary ridges in human beings consists of three main types, loop, whorl, arches, although various combination if these, and minor pattern variations in orientation, distortion, ridge width and number. These three major patterns & many other minor factors are determined by multi factorial inheritance along Mendelian lines, although prenatal disturbance of metabolism also affects their inheritance, as a result these findings may form a useful diagnostic tool in certain circumstances.1The present research is to study these patterns in patients with primary generalized epilepsy.

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Epilepsy in the families of epileptics

Cited by 16 publications

References 8 publications

Risk factors for childhood epilepsy: a case-control study from Irbid, Jordan

Risk factors for childhood epilepsy: a case-control study from Irbid, Jordan

Epilepsy prevalence in a rural area in Istanbul

Study of Dermatoglyphic Patterns of Digits in Patients with Primary Generalized Epilepsy

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