Epileptic seizure: An unusual presentation of takayasu arteritis

Sriskantharajah, Sunantha; Thambipillai, Peranantharajah; Nisahan, Balasingam

doi:10.4172/1758-4272.1000163

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Table 1 shows the criteria used by the American College of Rheumatology to classify TA. Other large vessel vasculitis, such as giant cell arteritis (GCA), systemic lupus erythematosus, syphilis, tuberculosis, and congenital connective tissue disorders, such as Marfan's syndrome, are in the differential diagnosis for TA [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Takayasu Arteritis Presenting As Epileptic Seizure: A Case Report

Shrestha¹,

Pandit²,

Kharel³

2022

Cureus

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Takayasu's arteritis is a chronic granulomatous large-vessel vasculitis condition that affects the large and medium-sized arteries, primarily the heart and its major vessels. The first symptoms and indicators of Takayasu arteritis differ because the afflicted arteries are heterogeneous. Furthermore, vascular lesions might be difficult to identify at first, further complicating diagnosis. Takayasu arteritis presenting as epileptic seizures is rare. Here, we discuss a 20-year-old female who presented with a brief period of unresponsiveness, followed by a tonic stiffening, limb jerks, a postictal period of fatigue, and temporal memory loss. During the acute phase of Takayasu arteritis, high-dose glucocorticoid therapy and immunosuppressive therapy were used to control inflammatory reactions. Her symptoms gradually improved, and she was discharged from the hospital after serial monitoring; her follow-up visits revealed no recurrence.

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Section: Discussionmentioning

confidence: 99%

Takayasu Arteritis Presenting As Epileptic Seizure: A Case Report

Shrestha¹,

Pandit²,

Kharel³

2022

Cureus

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“…Decreased blood flow resulting from steno-occlusive lesions and/or shifting of the blood flow (steal) is responsible for various TA-associated CNS manifestations [4]. Whereas convulsive syncope as an initial clinical presentation is extremely uncommon [8][9][10][11][12], several other neurological manifestations including headache, vertigo, organic confusion, dementia, meningitis, encephalitis, stroke, visual disturbances and intracranial aneurysms have been commonly associated with TA [4,6].…”

Section: Discussionmentioning

confidence: 99%

Takayasu Arteritis Mistaken for Epilepsy: A Case Presenting With Convulsive Syncope

Pallangyo¹,

Misidai²,

Hemed³

et al. 2020

J Med Cases

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Takayasu arteritis (TA) is a chronic inflammatory disease characterized by granulomatous vasculitis that predominantly manifests as panaortitis. This occlusive thromboaortopathy lacks pathognomonic features often resulting in a diagnostic dilemma leading to its underrecognition, misdiagnosis and delayed management. Although neurological manifestations are not uncommon in TA, convulsive syncope as an initial clinical presentation is extremely rare. We report a case of convulsive syncope as a manifesting symptom of TA. A 17-year-old male patient of African origin was referred to us from an upcountry regional hospital with a diagnosis of medically intractable epilepsy for cardiovascular review. He presented with a 28-week history of generalized tonic-clonic seizures followed by loss of consciousness. He denied history of recurrent headaches, fever, visual disturbances, arthralgias, claudication or unintentional weight loss. Physical examination revealed feeble left-sided brachial and radial pulses, elevated blood pressure, differences in blood pressure between arms and leftsided carotid and vertebral bruits. Computed tomography angiogram of his thoracic and abdominal aorta revealed changes suggestive of a diffuse arteritis. Additionally, magnetic resonance angiogram of the brain revealed total occlusion of the left common carotid, left internal carotid, left external carotid and left vertebral arteries. Based on the physical examination and radiological findings, we reached a diagnosis of TA. He was prescribed dexamethasone, methotrexate, acetylsalicylic acid and amlodipine. He had a remarkable recovery and was seizure-free for the last 5 months after discharge. TA may manifest with convulsive syncope mimicking epilepsy. Despite its rarity, presentations of this nature continue to challenge clinicians resulting in delayed diagnosis with irreversible life-threatening consequences to patients. In view of this, physicians should strive to take detailed history and perform thorough physical examination so as to timely pick the characteristic signs of TA especially in patients presenting with unanticipated symptoms.

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Epileptic seizure: An unusual presentation of takayasu arteritis

Cited by 2 publications

References 5 publications

Takayasu Arteritis Presenting As Epileptic Seizure: A Case Report

Takayasu Arteritis Presenting As Epileptic Seizure: A Case Report

Takayasu Arteritis Mistaken for Epilepsy: A Case Presenting With Convulsive Syncope

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