Epileptiform seizures revealing neurocysticercosis: report of two clinical cases in Libreville, Gabon

Okome-Nkoumou, Mml; Ondounda, M.; Dzeing-Ella, Arnaud; Mounguengui, D.; Madjinou, M I Nziengui; Clevenbergh, Ph; Magne, C; Nzenze, J. R.

doi:10.1258/td.2010.090493

Cited by 2 publications

(4 citation statements)

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“…We identified 40 published cases of patients co-infected with NCC and HIV that met the inclusion criteria (Supplementary Tab le) 22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 . The information used to characterize HIV and NCC diseases was heterogeneous between articles and frequently incomplete.…”

Section: Characteristics Of Ncc In Hiv-positive Patientsmentioning

confidence: 99%

“…Sex was reported for 30 cases 22,23,24,25,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 ; 10 (33.3%) were female and 20 (66.7%) male, while individual age (mean 34.8 ± 11.5; range 13-72) was reported for 25 cases 22,23,24,25,28,29,30,31,32,33,35,36,37,38,39,40,41,43 .…”

Section: Characteristics Of Ncc In Hiv-positive Patientsmentioning

confidence: 99%

“…Although the published literature was frequently incomplete, we assessed whether HIV seropositivity was associated with differences in number (single vs. multiple), location (parenchymal vs. extraparenchymal), and stage (vesicular, colloidal, calcified, mixed) of parasites. Results in HIV-positive patients 22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 were compared with different series of NCC patients without HIV 13,15,16,18,44 , and are presented in Table 3. Within the two groups of patients, the most frequent radiological presentation was multiple vesicular parasites located in the parenchyma.…”

Section: Effect Of Hiv On Ncc Symptoms Imaging Characteristics and mentioning

confidence: 99%

“…We compiled HIV/NCC cases in which response to treatment was specified 22,24,25,26,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 . Treatment consisted of surgery and/or cysticidal drugs.…”

Section: Effect Of Hiv On Ncc Symptoms Imaging Characteristics and mentioning

confidence: 99%

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Neurocysticercosis and HIV Infection: what can we learn from the published literature?

Vazquez¹,

Romo

Fleury³

2019

Arq. Neuro-Psiquiatr.

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Infections caused by the human immunodeficiency virus (HIV) and by the larvae of Taenia solium (i.e., cysticercosis) are still widespread in many developing countries. Both pathologies modify host immune status and it is possible that HIV infection may modulate the frequency and pathogeny of cysticercosis of the central nervous system (i.e., neurocysticercosis [NCC]). Objective: To describe published cases of NCC among HIV-positive patients and to evaluate whether the characteristics of NCC, including frequency, symptoms, radiological appearance, and response to treatment differed between HIV-positive and HIV-negative patients. Methods: Forty cases of NCC/HIV co-infected patients were identified in the literature. Clinical and radiological characteristics, as well as response to treatment, were compared with non-matching historical series of NCC patients without HIV infection. Results: Most of these patients had seizures and multiple vesicular parasites located in parenchyma. Clinical and radiological characteristics were similar between HIV-positive and HIV-negative patients with NCC, as well as between immunocompromised and non-immunocompromised HIV-positive patients. Conclusion: Our review did not reveal clear interactions between HIV and NCC. This may be partially due to the small number of cases and reliance on published research. A systematic, multi-institutional effort aiming to report all the cases of this dual pathology is needed to confirm this finding and to clarify the possible relationship between both pathogens.

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Section: Characteristics Of Ncc In Hiv-positive Patientsmentioning

confidence: 99%

Section: Characteristics Of Ncc In Hiv-positive Patientsmentioning

confidence: 99%

Section: Effect Of Hiv On Ncc Symptoms Imaging Characteristics and mentioning

confidence: 99%

“…We compiled HIV/NCC cases in which response to treatment was specified 22,24,25,26,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43 . Treatment consisted of surgery and/or cysticidal drugs.…”

Section: Effect Of Hiv On Ncc Symptoms Imaging Characteristics and mentioning

confidence: 99%

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Neurocysticercosis and HIV Infection: what can we learn from the published literature?

Vazquez¹,

Romo

Fleury³

2019

Arq. Neuro-Psiquiatr.

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Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa

et al. 2015

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BackgroundThis study aimed to map the distribution of Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa. These two major neglected tropical diseases are presumed to be widely distributed in Africa, but currently the level of co-distribution is unclear.MethodsA literature search on T. solium taeniosis/cysticercosis was performed to compile all known studies on the presence of T. solium and apparent prevalence of taeniosis and porcine cysticercosis in Africa. Studies were geo-referenced using an online gazetteer. A Bayesian framework was used to combine the epidemiological data on the apparent prevalence with external information on test characteristics to estimate informed district-level prevalence of taeniosis and porcine cysticercosis. Districts with T. solium taeniosis/cysticercosis presence were cross-referenced with the Global Neglected Tropical Diseases Database for schistosomiasis presence.ResultsThe search strategies identified 141 reports of T. solium in Africa from 1985 to 2014 from a total of 476 districts in 29 countries, 20 with porcine cysticercosis, 22 with human cysticercosis, and 16 with taeniosis, in addition to 2 countries identified from OIE reports. All 31 countries were considered, on national scale, to have co-distribution with schistosomiasis. Presence of both parasites was confirmed in 124 districts in 17 countries. The informed prevalence of taeniosis and porcine cysticercosis were estimated for 14 and 41 districts in 10 and 13 countries, respectively.ConclusionsWith the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests. In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.Electronic supplementary materialThe online version of this article (doi:10.1186/s13071-015-0938-7) contains supplementary material, which is available to authorized users.

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Epileptiform seizures revealing neurocysticercosis: report of two clinical cases in Libreville, Gabon

Cited by 2 publications

References 5 publications

Neurocysticercosis and HIV Infection: what can we learn from the published literature?

Neurocysticercosis and HIV Infection: what can we learn from the published literature?

Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa

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