Episodic memory development: Bridging animal and human research

Bevandić, Juraj; Chareyron, Loïc J.; Bachevalier, Jocelyne; Cacucci, Francesca; Genzel, Lisa; Newcombe, Nora S.; Vargha-Khadem, Faraneh; Ólafsdóttir, H. Freyja

doi:10.1016/j.neuron.2024.01.020

Cited by 6 publications

(1 citation statement)

References 207 publications

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“…Semantic memory is the declarative long-term memory that encompasses memory for concepts, facts, and the meanings of words and other acquired knowledge such as language, mathematics and so forth, and is the basis for nearly all human activity 22 . Episodic memory is the declarative long-term memory that involves the recollection of personal experiences or events, including the time and place one has personally experienced 23 .…”

Section: Memory Types and Our Experiments-both Semantic And Procedura...mentioning

confidence: 99%

Similarity-based retroactive interference in semantic and procedural long-term memories in human participants in real-life situations

2024

Preprint

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If memories of similar things are stored in the brain at about the same location or using a similar group of neurons and with similar neural networks, then a newly acquired memory will interfere with or even erase an old similar memory and lead to forgetting. We designed two experiments to test this hypothesis: a verbal experiment (for declarative semantic memory) and a gymnastic experiment (for nondeclarative procedural-related memory). In the verbal experiment, the participants first memorized two poem stanzas, then memorized two new stanzas that are very similar to the first two, and finally, took a test on the stanzas they memorized first. In the gymnastic experiment, the participants first learned a set of gymnastics, then learned another (very similar) set, and finally, took a test on the gymnastics set they learned first. The results showed that the participants who memorized two new poem stanzas made more mistakes than did the control participants in the last test, and the participants who learned a new set of gymnastics performed the first set much poorly compared with the control participants in the last test. We included an additional group in each experiment. The participants in this group were required to review the previously learned poem stanzas or gymnastics when they were learning the new ones (to compare the new ones with the old ones). The results showed that this group performed far better in the last test (on what they learned first). In summary, our experiments showed that newly acquired memories significantly interfered with or even erased similar old (semantic and procedural long-term) memories; nevertheless, if new things were learned in comparison with old ones, the interference could be noticeably reduced. Our study provided support for similarity-based retroactive interference in long-term semantic and procedural memories and offered ways to reduce such interference.

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Section: Memory Types and Our Experiments-both Semantic And Procedura...mentioning

confidence: 99%

Similarity-based retroactive interference in semantic and procedural long-term memories in human participants in real-life situations

2024

Preprint

View full text Add to dashboard Cite

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From animal models to human individuality: Integrative approaches to the study of brain plasticity

Hille,

Kühn,

Kempermann

et al. 2024

Neuron

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Memory engram stability and flexibility

Zaki,

Cai

2024

Neuropsychopharmacol.

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Many studies have shown that memories are encoded in sparse neural ensembles distributed across the brain. During the post-encoding period, often during sleep, many of the cells that were active during encoding are reactivated, supporting consolidation of this memory. During memory recall, many of the same cells that were active during encoding and reactivated during consolidation are reactivated during recall. These ensembles of cells have been referred to as the memory engram cells, stably representing a specific memory. However, recent studies question the rigidity of the “stable memory engram.” Here we review the past literature of how episodic-like memories are encoded, consolidated, and recalled. We also highlight more recent studies (as well as some older literature) that suggest that these stable memories and their representations are much more dynamic and flexible than previously thought. We highlight some of these processes, including memory updating, reconsolidation, forgetting, schema learning, memory-linking, and representational drift.

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Episodic memory development: Bridging animal and human research

Cited by 6 publications

References 207 publications

Similarity-based retroactive interference in semantic and procedural long-term memories in human participants in real-life situations

Similarity-based retroactive interference in semantic and procedural long-term memories in human participants in real-life situations

From animal models to human individuality: Integrative approaches to the study of brain plasticity

Memory engram stability and flexibility

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