Assertions of knowledge—that is, assertions which constitute ascriptions of knowledge—have served both as a central source of data in the epistemological theorizing and as an important target of such theorizing themselves. This chapter considers three issues concerning knowledge ascriptions that have figured prominently in recent discussion: their use as evidence for specific epistemological claims and theories, the pragmatics and psychology of knowledge ascriptions, and the social role(s) that the relevant assertions might play. There are important interactions among these topics; and they, and positions taken in response to them, interact as well with central questions about both assertion and linguistic communication generally. One central point on which epistemologists divide, however, is over how closely tied various features of our knowledge-attributing behavior are to semantics, or to (presumed) facts about assertion per se.