Epithelial microcysts

Efron, Nathan

doi:10.1016/b978-0-7020-4269-0.00017-1

Cited by 5 publications

(9 citation statements)

References 22 publications

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“…One 5‐MM subject was non‐compliant, with severe protocol deviation in lens handling (untrained domestic helper assisted with lens removal), and was excluded from the study after the 9‐month visit. One (3%) 6‐MM subject showed Grade 2 microcysts 36 at the 9‐month visit, which recurred at the 12‐month visit after resuming lens wear. Lens wear was terminated for this subject thereafter.…”

Section: Resultsmentioning

confidence: 99%

One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

Guo

Cheung

Kojima

et al. 2021

Ophthalmic Physiologic Optic

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Purpose: To present the 1-year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study, which aims to investigate the myopia control effect of orthokeratology (ortho-k) lenses with different back optic zone diameters (BOZD). Method: Children, aged 6 to <11 years, having myopia −4.00 D to −0.75 D, were randomly assigned to wear ortho-k lenses with 6 mm (6-MM group) or 5 mm (5-MM group) BOZD. Data collection included changes in refraction, vision, lens performance and binding, ocular health conditions, axial length and characteristics of the treatment zone (TZ) area. Results: The 1-year results of 34 and 36 subjects (right eye only) in the 6-MM and 5-MM groups, respectively, are presented. No significant differences in baseline demographics were found between the groups (p > 0.05). The first-fit success rates, based on satisfactory centration at the 1-month visit, were 100% and 94% respectively. Horizontal TZ size was 0.92 mm and 0.72 mm smaller in the 5-MM group at the 6-month and 12-month visits, respectively (p < 0.05). At the 12month visit, no significant between-group differences were found in the incidence of corneal staining (low grade only), lens binding and visual performance (all p > 0.05). Axial elongation was slower in the 5-MM group (0.04 AE 0.15 mm) than the 6-MM group (0.17 AE 0.13 mm) (p = 0.001). A significant positive correlation was observed between the horizontal TZ size and axial elongation (r = 0.36, p = 0.006). Conclusion: Clinical performance of the two ortho-k lenses was similar, indicating that a smaller BOZD (5 mm) did not affect lens performance or ocular integrity. However, a smaller BOZD led to a reduced TZ, with retardation of axial elongation by 0.13 mm compared to conventional 6 mm BOZD ortho-k lenses after one year of lens wear.

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Section: Resultsmentioning

confidence: 99%

One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

Guo

Cheung

Kojima

et al. 2021

Ophthalmic Physiologic Optic

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“…Epithelial microcysts are important indicators of chronic metabolic stress and are postulated to be cellular debris accumulated due to reduced metabolism induced by chronic hypoxia. 2 Previous studies in orthokeratology patients have reported either a mild 3 or absent 4-6 microcystic response. There do not appear to be any previously published reports of diffuse grade 4 microcysts after 18 months of orthokeratology lens wear.…”

Section: Discussionmentioning

confidence: 97%

“…Best-corrected visual acuity was 0.10 logMAR in each eye and no symptoms were reported. Slitlamp examination revealed grade 4 microcysts, 2 covering 70% to 80% of the cornea in both eyes (left eye more severe) ( Figure 2A). Sclerotic scatter slit lamp technique revealed the presence of concentric white oedematous rings, indicating loss of transparency (corneal haze) ( Figure 2B).…”

Section: Case Reportmentioning

confidence: 99%

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Microcystic corneal oedema associated with over-wear of decentred orthokeratology lenses during COVID-19 lockdown

Guo

Cho

Efron

2021

Clinical and Experimental Optometry

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“…Those with any active ocular surface disease, corneal opacities, glaucoma, use of medication that could affect the ocular physiology, or a history of any type of ocular surgery were excluded [15]. Before the eye examination, contact lens wear was discontinued for at least 2 days [16]. Only data from the right eye of each subject were chosen for the study analysis [17].…”

Section: Subjectsmentioning

confidence: 99%

The Repeatability and Agreement of Ocular Parameters Measured with the MYAH and Myopia Master Devices between Expert and Non-Expert Practitioners

Ortiz-Toquero,

Sanchez,

Gurrea

et al. 2024

Life

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In myopia control, it is essential to measure the axial length (AL) and corneal parameters, and to monitor whether changes in these parameters have occurred over time. The aim of this study was to analyse the repeatability and agreement between expert and non-expert practitioners in ocular parameters measured by the MYAH and Myopia Master. Three repeated measurements (n = 42) were recorded with the MYAH and Myopia Master by two (an expert and a non-expert) observers in a randomized order. The AL, K1, K2, and white-to-white (WTW) distance were collected. The intraobserver repeatability was excellent in all parameters measured with both devices in both observers. The AL outcome presented the best repeatability with the MYAH and Myopia Master (intraclass correlation coefficient, ICC = 1.0; coefficient of variation, CV ≤ 0.06% for both observers), while the WTW presented poorer results (ICC ≤ 0.991; CV ≤ 0.52%). The Myopia Master provides a significantly (p ≤ 0.01) flatter K1 and K2 as well as a lower WTW (p ≤ 0.01) than the MYAH. No statistically significant difference in AL measurements was found with either device (p ≥ 0.10; ICC = 1.0). None of the parameters showed differences (p ≥ 0.12) between the expert and non-expert observer. The MYAH and Myopia Master provide consistent measurements in a healthy adult population regardless of the previous clinical experience of the observer. AL measurements should be used interchangeably but K1, K2, and WTW should be used interchangeably with caution.

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Epithelial microcysts

Cited by 5 publications

References 22 publications

One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial

Microcystic corneal oedema associated with over-wear of decentred orthokeratology lenses during COVID-19 lockdown

The Repeatability and Agreement of Ocular Parameters Measured with the MYAH and Myopia Master Devices between Expert and Non-Expert Practitioners

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