Epithelioid hemangioendothelioma of the liver following contact with vinyl chloride

Gelin, Michel; Stadt, J. Van de; Rickaert, Fabienne; Prez, C. De; Levarlet, Micheline; Adier, M.; Lambillione, J.P.

doi:10.1016/0168-8278(89)90168-2

Cited by 54 publications

(30 citation statements)

References 18 publications

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“…Its unpredictable behaviour and prognosis raises controversy about the role of liver transplantation, especially in view of (a) the spontaneous, long-term survival [6,1,31; (b) the 28% to 45% incidence of extrahepatic, mostly pulmonary, osseous, peritoneal and/or lymph node disease [l, 3, 41; (c) the reported recurrent allograft disease [16,19,20,21,22,23,241.…”

Section: Discussionmentioning

confidence: 99%

Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation

et al. 2004

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Hepatic epithelioid haemangioendotheliomas (HEHEs) are rare, low-grade vascular tumours. transplantation Five adults with HEHEs and one adult with a vascular tumour showing combined features of haemangioma and haemangioendothelioma underwent liver transplantation. Two HEHE patients had extrahepatic metastases at the time of transplantation. Median survival time following diagnosis was 10.7 years (range 40 months to 195 months). One patient needed resection of a HEHE in the breast 13 years post-transplantation. All six patients are surviving free from disease 22 to 166 months after transplantation (median 77 months). One HEHE-patient who had been treated for 8 years for vertebral and cerebral localisations is free of disease without immunosuppression 56 months after transplantation. We can conclude that liver transplantation is a valuable treatment for hepatic haemangioendothelioma, even in cases of extrahepatic localisation of the disease.

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Section: Discussionmentioning

confidence: 99%

Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation

et al. 2004

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“…El HEE fue reportado por primera vez por Ishak, en 1984, en una serie de 32 pacientes (2)(3)(4)(5)(6). Desde entonces, ha sido descrito en órganos como el bazo, el hueso, las meninges, la mama, el corazón, el estómago y los nódulos linfáticos (6).…”

Section: Introductionunclassified

Trasplante hepático en hemangioendotelioma epitelioide: reporte de dos casos y revisión de la literatura

Zuluaga

Santos

Muñoz

et al. 2016

Rev. Colomb. Gastroenterol.

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El hemangioendotelioma epitelioide hepático es un tumor raro, de naturaleza agresiva y comportamiento impredecible, con una incidencia de menos de 1 caso por millón de personas al año. Se presenta espe- cialmente en mujeres jóvenes y con síntomas no específicos como dolor abdominal y pérdida de peso. La presentación radiológica es con múltiples nódulos o masas periféricas y bilaterales, con retracción de la cápsula, en algunos casos con calcificaciones y compromiso vascular. Debe realizarse biopsia hepática para confirmar el diagnóstico y para descartar diagnósticos alternativos como angiosarcoma, hepatocarcinoma, colangiocarcinoma y metástasis. El manejo depende de la extensión al momento de presentación, aunque solo el 10% de los casos es susceptible de resección. En las últimas décadas, el trasplante hepático se ha convertido en una opción de manejo, con series de casos aisladas reportadas por centros de trasplante en el mundo. En este artículo se presenta la experiencia de 2 pacientes con diagnóstico de hemangioendotelioma epitelioide hepático sin posibilidad de resección, confirmado histológicamente, sin compromiso extrahepático y que fueron llevados a trasplante de hígado exitoso y sin recurrencia de la enfermedad a 4 y 6 años después del trasplante.

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“…While resection is the most adequate treatment, transplantation is commonly performed, since HE often presents in a multinodular diffuse type (8)(9)(10)(11) …”

Section: Introductionmentioning

confidence: 99%

Selective intra-arterial Y-90 microsphe

Lacin

Küçük²,

Öz³

et al. 2011

Turk J Gastroenterol

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Epithelioid hemangioendothelioma of the liver following contact with vinyl chloride

Cited by 54 publications

References 18 publications

Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation

Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation

Trasplante hepático en hemangioendotelioma epitelioide: reporte de dos casos y revisión de la literatura

Selective intra-arterial Y-90 microsphe

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