2006
DOI: 10.1007/s00534-005-1021-0
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Epithelioid hemangioendothelioma of the liver

Abstract: Epithelioid hemangioendothelioma (EH) is a rare tumor of vascular origin, which occurs at sites such as soft tissues, liver, or lung, and has a highly unpredictable malignant potential. It is an intermediate entity between well-differentiated hemangioma and angiosarcoma. We present two cases of this rare disease in which the tumor was detected fortuitously and the definitive diagnosis was based on histological evidence. Both our cases are highly illustrative of the two ways in which hepatic EH can present (nod… Show more

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Cited by 21 publications
(20 citation statements)
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“…EHE is a rare tumor and often needs radiologic -pathologic correlation for diagnosis (1)(2)(3)(4). We faced with a large mass in the patient's liver but surprisingly he only presented with lungs metastatic symptom without any GI symptoms.…”
Section: Discussionmentioning
confidence: 99%
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“…EHE is a rare tumor and often needs radiologic -pathologic correlation for diagnosis (1)(2)(3)(4). We faced with a large mass in the patient's liver but surprisingly he only presented with lungs metastatic symptom without any GI symptoms.…”
Section: Discussionmentioning
confidence: 99%
“…Some clinicians recommended a definitive diagnosis by histopathology results because these signs aren't specific (1,4). EHE needs good core biopsy from target lesion and an expert pathologist.…”
Section: Discussionmentioning
confidence: 99%
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“…However, more ominous presentations with portal hypertension or hepatic failure have been described [Mehrabi et al 2006]. The most common physical finding is hepatosplenomegaly [Garcia-Botella et al 2006]. Possible associated exposures include oral contraceptive pills [Dean et al 1985], vinyl chloride [Shin et al 1991;Gelin et al 1989], hepatic trauma [Banerjee and Rennison, 1992], viral hepatitis [Lauffer et al 1996], and primary biliary cirrhosis [Terada et al 1989].…”
mentioning
confidence: 99%