Epithelioid Hemangioma Involving Three Contiguous Bones: a Case Report with a Review of the Literature

Abstract

An epithelioid hemangioma involving three contiguous bones in continuity has, to the best of our knowledge, not been reported in the literature. A case of a 48-year-old man presented with radiating pain to the lower thoracic region for two years. A radiograph and CT scan revealed both permeative osteolytic and multiple trabeculated lesions involving the left posterior part of the 10th rib as well as the 9th and 10th vertebral bodies in continuity and was misled as a malignant or infectious lesion. The histopathology and immuno-histochemistry of the lesion confirmed the diagnosis of an epithelioid hemangioma. The lesion was still stable as of three years after surgery.

An Unusual Case of Cavernous Hemangioma of the Rib in a Young Man with Lung Tuberculosis: A Brief Review and Case Report

“…Although radiological techniques provide complementary data on the differential diagnosis of hemangioma, performing a biopsy and/or surgical resection is essential for making a definite diagnosis (8). Our patient experienced hematoma of the rib during the biopsy procedure.…”

“…Cavernous hemangiomas are composed of dilated vessels lined by endothelial cells (7). These lesions originate from intraosseous tissue and form extraosseous components, leading to bone expansion (8). The agressive nature of bone hemangiomas can mimick that of malignant lesions (2).…”

Epithelioid Hemangioendothelioma of the Rib: A Rare Tumour with a Confusing Localization

“…In other cases reported in the literature, the radiologic findings were suggestive of malignant process, infectious disease, fibrous dysplasia or fibrous histiocytic lesions [5,6]. Positive diagnosis was based on microscopic findings, which consisted in single files, cords and small nests, typically lacking well-formed vascular channels, with only immature, intra-cytoplasmic lumina being observed.…”

Epithelioid hemangioendothelioma of the spine: results at seven years of average follow-up in a series of 10 cases surgically treated and a review of literature

“…Epithelioid hemangioma is multifocal in one-fifth of cases. Spine localization is exceptional [9,10]. Pain is the most common symptom experienced but it can also be asymptomatic [1].…”