Epithelioides Hämangioendotheliom der Wirbelsäule

Faust, Justus; Schmidt, Marcus; Eysel, Peer; Wanitschke, R.

doi:10.1007/pl00002171

Cited by 15 publications

(7 citation statements)

References 23 publications

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“…Other reports describe various vertebral columnar levels, including C5-6, T1, T11 and L2 [2,3,17,18]. In the case presented here, the tumor originated from L1.…”

Section: Discussionmentioning

confidence: 55%

“…Radiological findings showed a spinal mass originating from vertebra T1. She was operated twice but surgical excision of the infiltrating tumor in sano was not possible and she died four weeks after the second operation [2].…”

Section: Discussionmentioning

confidence: 99%

“…Prognosis of this tumor also depends on its histopathological features and location [2]. Surgical margins are important because positive margins lead to recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…It is therefore important to distinguish EHE from other subtypes of HE and epithelioid counterparts of hemangioma and angiosarcoma. EHEs affect all age groups and mostly originate from soft tissues of the extremities, lung and liver [1][2][3][4]. Bones, especially vertebrae, are rare presenting sites for these tumors.…”

Section: Introductionmentioning

confidence: 99%

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Epithelioid hemangioendothelioma derived from the spine region: Case report and review of the literature

Gökhan

Akyuz

Gürer

et al. 2006

Wien Klin Wochenschr

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Epithelioid hemangioendotheliomas (EHE) are rare vascular tumors which generally originate from soft tissues and visceral organs. Primary bone EHEs, especially those occurring in the spine region, are extremely rare. Our case is that of a 30-year-old man who was admitted to hospital with low back pain, difficulty in walking, post-voiding urinary incontinence and numbness in the caudal area. X-ray showed a lytic process affecting the vertebra L2 and collapse of L1. Vertebrectomy of L1 and gross total tumor resection were performed. Histopathological and immunohistochemical findings of the tumor tissue supported the diagnosis of EHE. The case, which to the best of our knowledge is only the fifth such reported case, is presented with its clinicopathological findings and a review of the literature.

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“…Other reports describe various vertebral columnar levels, including C5-6, T1, T11 and L2 [2,3,17,18]. In the case presented here, the tumor originated from L1.…”

Section: Discussionmentioning

confidence: 55%

Section: Discussionmentioning

confidence: 99%

“…Prognosis of this tumor also depends on its histopathological features and location [2]. Surgical margins are important because positive margins lead to recurrence.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Epithelioid hemangioendothelioma derived from the spine region: Case report and review of the literature

Gökhan

Akyuz

Gürer

et al. 2006

Wien Klin Wochenschr

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“…Luzzati et al (14) reported pathological fracture in eight out of ten cases in their series. Soft-tissue extensions can lead to neurologic compression, which result in neurologic symptoms such as paresthesia, weakness, and paraplegia (1,5,7,8,15,29,(32)(33)(34)36,(41)(42)(43)(44)(45).…”

Section: Clinical Presentationmentioning

confidence: 99%

Epithelioid hemangioendothelioma of the spine: case report and review of the literature

Albakr¹,

Schell²,

Drew³

et al. 2017

J. Spine Surg.

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Epithelioid hemangioendothelioma (EHE) has been described as a rare vascular bone lesion with histological features between hemangioma and high-grade angiosarcoma. Spinal EHE is a quite rare disease with few case reports and series reported in the literature. The tumor cells are positive for vimentin, CD31and The patient was started on local radiation therapy (RT). On follow-up, 3 months after the second surgery, the thoracic spinal pain had improved dramatically. Our review highlights the diagnosis, clinical presentation, and treatment of spinal EHE. Complete resection is associated with good outcome. Radiotherapy has been used in partially resected lesions. However, the role of radiotherapy as primary treatment is not yet defined.Further studies should develop a treatment algorithm for this rare tumour.

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Treatment of Primary Vertebral Tumors

Singh

Meyer

Jenkins

2009

Mount Sinai J Medicine

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Advances in the treatment of disease and detection through advanced imaging have led to an increase in the discovery of vertebral tumors. Although the majority of symptomatic spinal lesions are metastatic in origin, a significant number of them arise primarily in the spine. These lesions encompass a wide variety of tumor types classified by their cell of origin: bony tumors, cartilaginous tumors, vascular tumors, plasma cell dyscrasias, and tumors that arise from embryonic rests. Further classification of these tumors into malignant or benign subtypes is based on their clinical progression, histopathological evidence of invasiveness, and response to therapy. We provide a brief overview and description of primary tumors as well as treatment paradigms for the individual tumor types. Mt Sinai J Med 76:499-504, 2009. (c) 2009 Mount Sinai School of Medicine.

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Epithelioides Hämangioendotheliom der Wirbelsäule

Cited by 15 publications

References 23 publications

Epithelioid hemangioendothelioma derived from the spine region: Case report and review of the literature

Epithelioid hemangioendothelioma derived from the spine region: Case report and review of the literature

Epithelioid hemangioendothelioma of the spine: case report and review of the literature

Treatment of Primary Vertebral Tumors

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