Epithelioma Arising on Lupus Erythematosus

Squamous Cell Carcinoma Complicating Chronic Discoid Lupus Erythematosus (Cdle)

“…The appearance of well-differentiated squamous cell carcinoma in chronic discoid lupus erythematosus is undoubtedly infrequent, but well-reported (1,3,4,8). Considerable emphasis has been laid on the participation of scarring in its development in various conditions, namely lupus vulgaris, donovanosis, burns, fistulae, and discoid lupus erythematosus.…”

“…Farah et al (3) supported this by location of the growth over sun-exposed areas in a large majority of such subjects, and by histological evidence of actinic damage in the form of dyskeratosis and proliferation of the epidermis into the dermis. Radiotherapy (6) and arsenical treatment (8) have also been implicated. In our patients and those reported by Millard and Barker (4), no such predisposition was found.…”