Epoxy Functional Porous POSS Microparticle Synthesis

Abstract

Epoxy-functional porous polyhedral oligomeric silsesquioxane (POSS) microparticles were synthesized by templated polymerization in two-steps by using monodisperse 2µm poly(GMA) seed latex particles as a template. In the first step, templated polymer latex was swollen in emulsion medium to obtain micron size porous POSS particles. In the second step, the hydrophobic monomers metharcyl-POSS, epoxy-functional monomer glycidyl methacrylate (GMA), the crosslinking agent GDMA and the thermal imitator diffused into the swollen template in emulsion medium for free-radical polymerization. The resultant poly(POSS-co-GDMA-co-GMA) microparticles were obtained in polydisperse form due to the high molecular weight of the silica cage core of POSS created difficulty in the diffusion step. However; monodisperse composite microparticles were obtained around 5.8 ± 0.4µm in size via centrifugal post-separation. The spherical fine porous hybrid structure was fully characterized as morphological, thermal, chemical composition, and crystalline form by SEM, TGA, FTIR, and XRD respectively.

Biosensor for ATP detection via aptamer-modified PDA@POSS nanoparticles synthesized in a microfluidic reactor

“…4 C). The peak at 1100 cm -1 represents inorganic cage structure [ 45 , 46 ]. The peaks of the organic part were for the C=O stretching at 1730 cm -1 , stretching at 2950 cm -1 and 2890 cm -1 [ 45 , 46 ].…”

“…The peak at 1100 cm -1 represents inorganic cage structure [ 45 , 46 ]. The peaks of the organic part were for the C=O stretching at 1730 cm -1 , stretching at 2950 cm -1 and 2890 cm -1 [ 45 , 46 ]. The hybrid organic-inorganic structure of POSS nanoparticles can be easily functionalized with various molecules such as antibodies, aptamers, or peptides to bind ATP selectively.…”