EPR Spectra and covalency of bis(amidinourea/O-alkyl-1-amidinourea)copper(II) complexes Part II. Properties of the CuN42− chromophore

Ray, R.K.; Kauffman, George B.

doi:10.1016/s0020-1693(00)80215-7

Cited by 182 publications

(41 citation statements)

References 34 publications

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“…The spectrum of the four coordinated C8 in frozen DMSO resolved four copper hyperfine lines, characteristic of monomeric copper(II) complexes [35]. The observed ‖ > ⊥ > (2.0023) values indicate that the unpaired electron is predominantly in the 2 − 2 orbital giving a 2 B 1 ground state [36,37] and the complexes have distorted square planar geometry. For C6 and C7, the -values are <4, suggesting the monomeric nature of copper(II) centres and consistent with a 2 − 2 ground state having a small exchange coupling in the solid state while for C8, = 4.7 indicates that there are no spin exchange interactions between the copper centres in solution [38].…”

Section: Synthesis and Characterizationmentioning

confidence: 99%

Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

Pulipaka

Singh

Prajapati

et al. 2014

Advances in Chemistry

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A series of isonicotinoyl hydrazones have been synthesized via template method and were complexed to Cu(II). The ligands are coordinated to Cu(II) ion through the enolic oxygen and azomethine nitrogen resulting in a square planar geometry. The CT-DNA and bovine serum albumin binding propensities of the compounds were determined spectrophotometrically, the results of which indicate good binding propensity of complexes to DNA and BSA with high binding constant values. Furthermore, the compounds have been investigated for their cytotoxicities on A549 human lung cancer cell. Also the mode of cell death was examined employing various staining techniques and was found to be apoptotic.

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Section: Synthesis and Characterizationmentioning

confidence: 99%

Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

Pulipaka

Singh

Prajapati

et al. 2014

Advances in Chemistry

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“…The observed g || (2.2569) value for the complex is less than 2.3 suggesting a significant covalent character of the metalligand bond. The trend g || (2.2569) > g ⊥ (2.0225) >g e (2.0023) observed for the complex suggests that the unpaired electron is localized in the d x 2 −y 2 orbital of the copper(II) ion [18]. The axial symmetry parameter G is defined [19] as…”

Section: Esr Spectramentioning

confidence: 99%

Synthesis, spectral characterization, redox and antimicrobial activity of Schiff base transition metal(II) complexes derived from 4-aminoantipyrine and 3-salicylideneacetylacetone

Raman¹,

Thangaraja²,

Johnsonraja³

2005

Open Chemistry

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A novel tetradentate N 2 O 2 type Schiff base, synthesized from 1-phenyl-2,3-dimethyl-4-aminopyrazol-5-one(4-aminoantipyrine) and 3-salicylidene-acetylacetone, forms stable complexes with transition metal ions such as Cu II , Ni II , Co II and Zn II in ethanol. Microanalytical data, magnetic susceptibility, IR, UV-Vis., 1 H-NMR, ESR and Mass spectral techniques were used to confirm the structures. Electronic absorption spectra of the complexes suggest a square-planar geometry around the central metal ion. These complexes show higher conductance values, supporting their electrolytic nature. The monomeric nature of the complexes was confirmed from their magnetic susceptibility values. Cyclic voltammogram of the copper(II) and nickel(II) complexes in DMSO solution at 300 K were recorded and the results are discussed. The X-band ESR spectra of the copper complex were recorded and the molecular orbital coefficient values were calculated from the spectra. The in vitro antimicrobial activities of the investigated compounds were tested against bacteria such as Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and fungi like Aspergillus niger and Rhizoctonia bataicola. Most of the metal chelates show higher antimicrobial activity for the above microorganisms than that of the free ligand.

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“…The ν(C-S) stretching frequency of the thiazole ring was appeared at 780 cm -1 and it was shifed to 775-765 cm -1 region due to chelation. This is further supported by the appearance of new bands at 518-513 and 462-442 cm -1 region attributed to ν(M-N) and ν(M-S) frequencies, respectively in all the metal chelates [32].…”

Section: Resultsmentioning

confidence: 54%

Biological Screening Studies of DNA Relate Metal Complexes from Benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole

Palanimurugan¹,

Kulandaisamy²

2018

Asian J. Chem.

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Novel terdentate cationic complexes of Cu(II), Ni(II), Co(II), Mn(II) and Zn(II) ion have been prepared using a Schiff base derived from benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole. The structural features of metal-chelates have been confirmed by micro-analytical data, FAB-Mass spectra, powder XRD, SEM, FTIR, UV-visible, 1 H NMR, EPR, CV and thermal analysis techniques. The analytical data of the complexes correspond well with the general formula [ML2]Cl2. The high conductance data of metal chelates supports their 1:2 electrolytic nature. The magnetic susceptibility and electronic absorption spectra of the complexes indicate that all the metal-chelates exhibit octahedral geometry around the central metal ion. Powder XRD data and SEM images persist that the complexes are nano size grain with polycrystalline structure. DNA interaction studies of [CuL2]Cl2 complex have been done by electronic spectral and cyclic voltammetric measurements which revealed that the binding occurs through intercalation between complex and DNA interaction of [CuL2]Cl2 complex with CT-DNA leads to hypochromism. The MIC values against the growth of microorganisms are lower for metal chelates than the ligand. This is mainly due to lipophilicity of metal ion in complexes.

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EPR Spectra and covalency of bis(amidinourea/O-alkyl-1-amidinourea)copper(II) complexes Part II. Properties of the CuN42− chromophore

Cited by 182 publications

References 34 publications

Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

Cu(II) Complexes of Isoniazid Schiff Bases: DNA/BSA Binding and Cytotoxicity Studies on A549 Cell Line

Synthesis, spectral characterization, redox and antimicrobial activity of Schiff base transition metal(II) complexes derived from 4-aminoantipyrine and 3-salicylideneacetylacetone

Biological Screening Studies of DNA Relate Metal Complexes from Benzylidene-4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one and 2-aminothiazole

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