2012
DOI: 10.2169/internalmedicine.51.6768
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Epstein-Barr Virus Encephalitis with a Reversible Splenial Lesion

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Cited by 3 publications
(6 citation statements)
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“…Gastrointestinal manifestations are frequently present, characterised by elevation in transaminases, abdominal pain, hepato‐splenomegaly and less commonly acute fulminant hepatitis . In rare cases, neurological complications associated with EBV have been described involving encephalitis, transverse myelitis and cranial neuropathy . However, the simultaneous involvement of encephalitis and hepatitis by the EBV has not been documented to our knowledge.…”
supporting
confidence: 72%
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“…Gastrointestinal manifestations are frequently present, characterised by elevation in transaminases, abdominal pain, hepato‐splenomegaly and less commonly acute fulminant hepatitis . In rare cases, neurological complications associated with EBV have been described involving encephalitis, transverse myelitis and cranial neuropathy . However, the simultaneous involvement of encephalitis and hepatitis by the EBV has not been documented to our knowledge.…”
supporting
confidence: 72%
“…Interestingly, our case of EBV encephalitis was remarkably similar to the MRI feature of mild encephalitis with a reversible splenial lesion with reduced diffusion and apparent diffusion coefficient values in the corpus callosum, especially in the splenium, sometimes related to symmetrical white-matter lesions. [6][7][8][9][10] Viral and bacterial infections implicated in MERS have been reported, and most common pathogens are influenza virus A/B and the mumps virus. [6][7][8] Recently, EBV was documented in the pathogenesis of MERS; 6,10 however, a case of primary EBV infection presenting as both MERS and fulminant hepatitis has not yet been reported.…”
mentioning
confidence: 99%
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“…Among the rare adult case reports, we found two cases of EBV encephalitis, 9 , 10 one of tick-borne encephalitis (CSF WBC 33/μL), 13 one of anti-Yo rhombencephalitis, 14 one of viral encephalitis of unknown etiology (CSF WBC 408/μL), 15 one of influenza virus A encephalitis, one of HIV encephalitis, and some cases of MERS associated with systemic infections. 11 , 16 , 17 Among these cases, CSF WBC count and protein level were both unremarkable. Alleviation of clinical symptoms and imaging changes were achieved within a short period of time.…”
Section: Discussionmentioning
confidence: 90%
“…The abnormal signal intensity in the SCC resolved after 16 days of treatment. 16 An 8-year-old Chinese girl was admitted with generalized tonic–clonic seizures and mental deterioration following 1 day of prodromal symptoms consisting of severe headache with vomiting and high fever (40.0°C). 17 CSF showed an abnormal cell count (125×10 6 cells/L, 75% lymphocytes) and protein level of 11 mg/dL.…”
Section: Discussionmentioning
confidence: 99%