Eq-5d-5l

Herdman, Michael; Gudex, Claire; Lloyd, Andrew; Janssen, Mathieu F.; Kind, P; Parkin, David; Bonsel, GJ; Badia, X

doi:10.1037/t63848-000

Cited by 41 publications

(37 citation statements)

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“…Of the five King's stages, each one is associated with the number of regions involved and classified as follows: stage 1 one functional region involved; stage 2 two regions; stage 3 three regions; stage 4A corresponds to nutritional failure (gastrostomy); stage 4B to respiratory failure and the indication of assisted ventilation; stage 5 corresponds to death. Health-related quality of life (HRQoL) and health status were measured by the EuroQol Group EQ-5D-5L™ in the five dimensions Mobility, Self-Care, Usual Activities, Pain/Discomfort and Anxiety/Depression [22,23].…”

Section: Data Collectionmentioning

confidence: 99%

Costs of illness in amyotrophic lateral sclerosis (ALS): a cross-sectional survey in Germany

Osmanovic

Müschen

et al. 2020

Preprint

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Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder. Consequently, patients undergo a multidisciplinary treatment that often requires intensive use of medical resources. This study provides an estimate on the cost of illness depending on the clinical severity while also analysing the patients’ health-related quality of life.Methods Data from patients and caregivers was collected through a standardized questionnaire. Direct medical, direct non-medical and indirect costs were calculated using the latest German health economic guidelines. Patients were divided into five groups according to the King’s staging system. Health-related quality of life was assessed using EuroQoL Group EQ-5D-5LTM questionnaire. Influencing factors on both, total cost and quality of life, were examined.Results The mean annual total cost of illness was 78,256€ per patient while the lifetime cost per patient was estimated at 246,184€. The prevalence based total burden yearly therefore was 519,776,352€ in Germany. Nearly half of the costs were attributable to informal care. With increase of the clinical severity stage, costs rose and quality of life decreased. The score of the revised Amyotrophic Laterals Sclerosis Functional Rating Scale was identified as one major influencing factor on total costs, while subjective impairment in daily activities and classification into a care level influenced patients’ quality of life.Conclusion It is essential to understand the socioeconomic burden of a disease. These data can be used to improve patient care standards and quality of life while also serving as a basis for cost-benefit analyses during the approval process of new treatments.

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Section: Data Collectionmentioning

confidence: 99%

Costs of illness in amyotrophic lateral sclerosis (ALS): a cross-sectional survey in Germany

Osmanovic

Müschen

et al. 2020

Preprint

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show abstract

“…It comprises the following 5 dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and unable to/extreme problem 29 .…”

Section: Euroqol 5 Dimensions (Eq-5d) 29mentioning

confidence: 99%

Treatment strategies aiming at minimal disease activity in psoriatic arthritis

Vis¹

2019

http://isrctn.com/

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“…The researchers will collect the information on subjective quality of life (MANSA, Priebe et al, 1999) and health-related quality of life (EQ-5D-5L, Herdman et al, 2011). Loneliness will be assessed through the UCLA-8 loneliness scale (Hays and DiMatteo, 1987).…”

Section: Quality Of Life and Loneliness Assessmentsmentioning

confidence: 99%