EQ-5D-5L Valuation for the Malaysian Population

Shafie, Asrul Akmal; Thakumar, Annushiah Vasan; Lim, Ching Jou; Luo, Nan; Rand‐Hendriksen, Kim; Yusof, Farida Zuraina Mohd

doi:10.1007/s40273-018-0758-7

Cited by 62 publications

(56 citation statements)

References 29 publications

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“…50 Following previous research, different models will be assessed including either the cTTO data, or combining the cTTO and DCE data in a hybrid model, and the results compared for adequacy with those for existing national value sets. [14][15][16][17][18][19][20][21][22][23][24][25] Modelling of values for the national value set will exclude valuations from respondents recruited from locations specifically for the collection of experience-based values and the valuations of respondents' own health state. Subgroup analysis will identify variables contributing to health state valuation in the Norwegian population.…”

Section: Discussionmentioning

confidence: 99%

Elicitation of Norwegian EQ-5D-5L values for hypothetical and experience-based health states based on the EuroQol Valuation Technology (EQ-VT) protocol

et al. 2020

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IntroductionNorway is one of several European countries that lacks a national value set and scoring algorithm for the EuroQol five dimensions (EQ-5D). Recent studies have found differences between countries in terms of health values or preferences for health states described by instruments such as the EQ-5D. The project aims to model a national value set for the five level version of the EQ-5D based on values elicited from a representative sample of the Norwegian adult general population in terms of region, age, sex and level of education. Using a sampling strategy supporting the collection of values for both hypothetical and experienced health states, the study will have the additional aim of assessing the feasibility of collecting experience-based values in accordance with the latest EQ-5D valuation study protocol, and comparing values with those given for hypothetical health states.Methods and analysisMultistage random sampling and quota-sampling will contribute to representativeness. To increase the number of valuations of experienced health states, those with less than perfect health will be oversampled, increasing the total number of interviews from 1000 to 1300–1500. The most recent EQ-5D valuation protocol will be followed which includes computer assisted face-to-face, one-to-one interviews and use of composite time trade-off and discrete choice experiments.Ethics and disseminationThe study has been reviewed and found to be outside of the scope of the ethics committee and thus not in need of ethical approval. The study findings will be disseminated through peer-reviewed publications, conference presentations and summaries for key stakeholders and partners in the field. The scoring algorithms will be available for widely used statistical software.

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Section: Discussionmentioning

confidence: 99%

Elicitation of Norwegian EQ-5D-5L values for hypothetical and experience-based health states based on the EuroQol Valuation Technology (EQ-VT) protocol

et al. 2020

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“…For example, the level-scale model 39 assumes the disutilities associated with increasing levels are the same across dimensions, up to a multiplicative constant, and the model has been found to outperform the main effects model in Spanish, Singaporean, Chinese, and Malaysian valuation studies. 12,39,40 These are no longer linear models and were hence beyond the scope of our analysis; however, we hypothesize that these more parsimonious models may be more amenable to introducing random effects for each parameter and may hence capture the correlation structure in the data more accurately.…”

Section: Discussionmentioning

confidence: 99%

“…To do this, analysts have assumed that β DCE = θ β TTO for some scalar θ . 6–15 The usual hybrid model then multiples the likelihoods for the Tobit and conditional logit and maximizes it over β TTO , σ 2 , and θ . 32…”

Section: Methodsmentioning

confidence: 99%

Using Both Time Tradeoff and Discrete Choice Experiments in Valuing the EQ-5D: Impact of Model Misspecification on Value Sets

et al. 2020

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Introduction. The EQ-5D-5L valuation protocol contains both time tradeoff (TTO) tasks and discrete choice experiments (DCE), raising the question of how to best use these in creating a value set. The hybrid model, which combines TTO and DCE data, has emerged as a commonly used approach. However, this model assumes independence among responses from the same individual, a linear relationship between TTO and DCE utilities, and, in many implementations, homoscedastic residuals. The aims of this study are to examine alternatives to these assumptions and determine the impact of misspecification on value sets. Methods. We performed a simulation study, parameterized using the US EQ-5D-5L valuation study, to assess the impact of model misspecification. We simulated TTO and DCE data with nonlinear relationships between TTO and DCE utilities, heteroscedastic errors, and correlated responses. Simulated data were analyzed using hybrid models with and without heteroscedasticity, Tobit models with and without heteroscedasticity, a latent class model, and a mixed model. Results. Mean absolute errors (MAEs) for correctly specified models were <0.05, whereas models that incorrectly assumed a linear relationship between TTO and DCE utilities or homoscedasticity of TTO responses featured states with an MAE >0.1. When a linear relationship between TTO and DCE utilities held, using both TTO and DCE data under correct specification yielded smaller MAEs compared with using TTO data alone but yielded larger MAEs when a linear relationship did not hold. Mistakenly assuming homoscedasticity led to increased MAEs, whereas ignoring dependence did not. Conclusions. Because heteroscedasticity in TTO utilities and nonlinear associations between DCE and TTO utilities have been noted, we recommend careful assessment of scedasticity and linearity to ascertain the suitability of a hybrid model.

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“…Patients mark each dimension on a scale of 1 "no problem" to 5 "worst problem". The five-digit number (ranging from 11,111 to 55,555) obtained was then converted to a utility index based on EQ-5D-5 L value set for Malaysia [23]. For EQ-VAS participants were asked to mark their health on a vertical visual analogue scale from 0 (worst possible health) to 100 (best possible health).…”

Section: Health Status Measuresmentioning

confidence: 99%

Validation and clinical interpretation of the St George’s respiratory questionnaire for COPD (SGRQ-C) after adaptation to Malaysian language and culture, in patients with COPD

Rehman

Hassali

Harun

et al. 2020

Health Qual Life Outcomes

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Background: Cultural differences affect the administration and results of health status questionnaires. "Cross cultural adaptation" ensures retention of psychometric properties such as validity and reliability at an item and/or scale level. Objective: To develop a Malaysian version of St George's respiratory COPD specific questionnaire (SGRQ-CM), to evaluate the full spectrum of psychometric properties (reliability, validity and responsiveness), to test the factor structure and to assess minimum clinically important difference for the SGRQ-CM, to be used in population of Malaysia. Methodology: SGRQ-C was translated to Bahasa Malaysia using a standard protocol. 240 COPD patients were included in the study. All patients were followed-up for six months. Construct validity, internal consistency, item convergent validity, test-retest ability, responsiveness, factor analysis and MCID of the Malaysian version of SGRQ-C to be used in population of Malaysia were evaluated. Results: The Cronbach alpha coefficient and intraclass correlation coefficients (ICC) for SGRQ-CM were reported as 0.87, and 0.88 respectively. Correlation of SGRQ-CM with CAT, EQ-5D-5 L, mMRC dyspnea scales and FEV 1 %predicted were reported as 0.86, − 0.82, 0.72 and − 0.42 respectively. Correlation coefficient between the subscales and other clinical and health status measures ranged from r = − 0.35 to r = − 0.87. The MCID was reported as 5.07 (− 2.54-12.67). Conclusion: The Malaysian version of SGRQ-C has a good psychometric property comparable to those of the original version and has a strong evidence of validity, reliability and responsiveness towards disease severity in Malaysian COPD patients. It can be recommended as a reliable quality of life measure for future research.

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EQ-5D-5L Valuation for the Malaysian Population

Cited by 62 publications

References 29 publications

Elicitation of Norwegian EQ-5D-5L values for hypothetical and experience-based health states based on the EuroQol Valuation Technology (EQ-VT) protocol

Elicitation of Norwegian EQ-5D-5L values for hypothetical and experience-based health states based on the EuroQol Valuation Technology (EQ-VT) protocol

Using Both Time Tradeoff and Discrete Choice Experiments in Valuing the EQ-5D: Impact of Model Misspecification on Value Sets

Validation and clinical interpretation of the St George’s respiratory questionnaire for COPD (SGRQ-C) after adaptation to Malaysian language and culture, in patients with COPD

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