Based on a spin-dependent Boltzmann-Uehling-Uhlenbeck transport model with spin-dependent potentials incorporated using the lattice Hamiltonian method, we have studied the global spin polarization perpendicular to the reaction plane as well as the local spin polarization in the longitudinal direction in non-central intermediate-energy heavy-ion collisions, as an extension of similar studies in relativistic heavy-ion collisions. Both the global and the local spin polarizations are found to be mostly dominated by the time-odd component of the nuclear spin-orbit potential. Impacts of various theoretical uncertainties on the nucleon spin polarization as well as its dependence on the beam energy and impact parameter are discussed. Our study serves as a baseline for understanding the spin polarization mechanism of strongly interacting matter produced in heavy-ion collisions dominated by nucleon degree of freedom.The spin physics is an interesting topic in various fields. Due to the spin-orbit coupling, the spin polarization phenomena can generally be induced in a vorticity field. In non-central relativistic heavy-ion collisions, it was pointed out [1] that the produced quarkgluon plasma can be globally polarized perpendicular to the reaction plane, as a result of the angular momentum transfer from colliding nuclei to the midrapidity region. This can lead to the spin polarization of Λ hyperons or vector mesons, whose polarizations can be experimentally measurable through the angular distribution of their decay. Although the experimentally measured spin polarizations of these particles are small at ultrarelativistic energies [2-4], they become considerably larger at lower collision energies [5]. Theoretical efforts based on transport models or hydrodynamic models have been devoted to predict [1,6] or explain [7-10] the spin polarization phenomena, showing that the quark-gluon plasma can be the most vortical fluid on the earth. Besides the global spin polarization, theorists have more recently predicted that there could be some local structures of the vorticity field [11], and they can lead to the azimuthal angular dependence of the longitudinal spin polarization [12][13][14]. However, the latest experimental data from the STAR Collaboration shows a different azimuthal angular dependence [15] compared to most theoretical studies. These spin polarization phenomena in heavy-ion collisions serve as good probes of understanding the vortical dynamics in the strongly interacting matter as well as the properties of the spin-orbit coupling.In intermediate-energy heavy-ion collisions, one expects that the spin polarization phenomena should exist as well, as a result of the nuclear spin-orbit interaction, which was first proposed to explain the magnetic number of finite nuclei [16,17]. Except for the well-known importance of the nuclear spin-orbit coupling in nuclear struc- * corresponding author: xujun@zjlab.org.cn ture studies, it also has dramatic dynamic effects in lowand intermediate-energy heavy-ion collisions (see, e.g., Ref...