Equine nonneoplastic abnormal ovary in a draft mare with high serum anti-Müllerian hormone: a case study

Abstract

We performed a standing hand-assisted laparoscopic ovariectomy in a draft mare that presented with high serum anti-Müllerian hormone (AMH) level and had an enlarged single cystic ovary. Histopathological examination revealed no tumor cell proliferation in the ovary, but the presence of a large ovarian cyst was confirmed. In the diagnosis of abnormal ovaries in mares, a comprehensive assessment should be performed, including the monitoring of ovarian morphology and biomarkers over time, to determine the disease prognosis and treatment plan. The case of this mare with a nonneoplastic abnormal ovary and increased serum AMH level was rare. We suggest that standing hand-assisted laparoscopic ovariectomy is useful for the removal of large ovaries in draft mares.

Behavioral Disorders in Mares with Ovarian Disorders, Outcome after Laparoscopic Ovariectomy: A Case Series

“…Granulosa cell tumors and GTCTs are common ovarian neoplasms accounting for 2.5% of all neoplasms in horses [ 14 ]; they affect mares of all ages, may be unilateral or bilateral, and are rarely malignant. They are responsible for stallion-like behavior, poor breeding performances and infertility, aggressiveness, prolonged estrus, and poor behavior under the saddle [ 13 , 15 ].…”

Immunohistochemical markers for equine granulosa cell tumors: a pilot study

“…In horses, GCTs are usually unilateral and benign. Bilateral, malignant, and metastasizing tumors are rare but do occur [ 11 , 19 , 22 , 23 , 24 , 36 , 40 ]; however, potentially relevant markers are lacking. The proliferation marker Ki-67 is widely used in tumor assessment, and the proliferation rate has generally been shown to correlate with tumor progression, metastasis, and prognosis [ 1 , 5 ].…”