Equity in vaccination policies to overcome social deprivation as a risk factor for invasive meningococcal disease

Taha, Muhamed-Kheir; Martinón-Torres, Federico; Köllges, Ralph; Bonanni, Paolo; Sáfadi, Marco Aurélio Palazzi; Booy, Robert; Smith, Vinny; Garcia, Stephanie; Bekkat-Berkani, Rafik; Abitbol, Véronique

doi:10.1080/14760584.2022.2052048

Cited by 24 publications

(18 citation statements)

References 95 publications

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“…This situation further aggravates the inequity that already exists in terms of protection against meningococcal disease based on the public funding of the vaccines according to the region [ 36 ]. Therefore, introduction of a vaccine into the NIP and clear recommendations from health authorities are likely to increase vaccine uptake and promote equity [ 8 , 34 ].…”

Section: Discussionmentioning

confidence: 99%

“…Immunization is the most effective strategy for the prevention of meningococcal disease [ 5 ], and good safety profile of the universal mass vaccination has been demonstrated [ 6 ]. Two recombinant vaccines against MenB are available (4CMenB, Bexsero, GSK; and MenB-fHbp, Trumenba, Pfizer) [ 7 , 8 ], whether for private purchase in several countries or through publicly funded national immunization programs (NIPs) in countries such as Czech Republic, Ireland, Italy, Lithuania, Malta, Portugal [ 9 ], and the UK [ 10 ]. While the Spanish Association of Pediatrics has been advocating for it since 2014 [ 8 ], vaccination against MenB is not yet part of the NIP in Spain.…”

Section: Introductionmentioning

confidence: 99%

“…Two recombinant vaccines against MenB are available (4CMenB, Bexsero, GSK; and MenB-fHbp, Trumenba, Pfizer) [ 7 , 8 ], whether for private purchase in several countries or through publicly funded national immunization programs (NIPs) in countries such as Czech Republic, Ireland, Italy, Lithuania, Malta, Portugal [ 9 ], and the UK [ 10 ]. While the Spanish Association of Pediatrics has been advocating for it since 2014 [ 8 ], vaccination against MenB is not yet part of the NIP in Spain. However, it is funded by several autonomous regions, including the Canary Islands, Castilla y León, and, most recently, Catalonia, Andalucía [ 8 ], and Galicia [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…While the Spanish Association of Pediatrics has been advocating for it since 2014 [ 8 ], vaccination against MenB is not yet part of the NIP in Spain. However, it is funded by several autonomous regions, including the Canary Islands, Castilla y León, and, most recently, Catalonia, Andalucía [ 8 ], and Galicia [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Societal Preferences for Meningococcal B Vaccination in Children: A Discrete Choice Experiment in Spain

et al. 2022

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Introduction Immunization is the most effective strategy for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B (MenB); however, parents need to weigh the risk–benefit and financial impact of immunizing their children against MenB in the absence of a national immunization program (NIP). This study aimed to explore societal preferences (of parents and pediatricians) regarding the attributes of a MenB vaccine in Spain. Methods A discrete choice experiment (DCE) based on cross-sectional surveys was carried out to determine preferences. A literature review and scientific committee determined the six attributes related to the MenB vaccine included in the DCE: vaccination age, cost, duration, percentage of protection, adverse events probability, and expert/authority recommendation. Data were analyzed using a mixed logit model. Relative importance (RI) of attributes was calculated and compared between parents and pediatricians. Results A total of 278 parents [55.8% female, mean age 40.4 (standard deviation, SD 7.3) years] and 200 pediatricians [73.0% female, mean age 45.8 (SD 12.9) years] answered the DCE. For parents, the highest RI was attributed to vaccine cost, expert/authority recommendation, and percentage of protection (26.4%, 26.1%, and 22.9%, respectively), while for pediatricians the highest RI was assigned to percentage of protection, expert/authority recommendation, and vaccination age (27.2%, 23.7%, and 22.6%, respectively). Significant differences between parents and pediatricians were found in the RI assigned to all attributes ( p < 0.001), except for vaccine recommendation. Conclusion In the decision regarding MenB vaccination, cost was a driver in parental decision-making but had a low RI for pediatricians and, conversely, vaccination age was highly valued by pediatricians but was the attribute with least importance for parents. Despite these differences, expert/authority recommendation and percentage of protection were essential criteria for both groups. These results provide relevant information about MenB vaccination, highlighting the importance of considering societal preferences for NIP inclusion. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1007/s40121-022-00708-7.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Societal Preferences for Meningococcal B Vaccination in Children: A Discrete Choice Experiment in Spain

et al. 2022

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“…Several publications have suggested that the suboptimal uptake of the two types of meningococcal vaccines available in the US (MenACWY and MenB) may be related to inequities or disparities in awareness or access to these vaccines in adolescents and young adults of different racial or ethnic groups, socioeconomic groups, in different geographic areas in the US [ 15 , 16 , 17 , 18 , 19 , 20 ]. For example, Pruitt et al [ 20 ], using the NIS-Teen data showed disparities in the uptake of the second dose of MenACWY vaccine by race/ethnicity and insurance status.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Social Determinants of Health on Meningococcal Vaccination Awareness, Delivery, and Coverage in Adolescents and Young Adults in the United States: A Systematic Review

et al. 2023

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Vaccines remain a fundamental intervention for preventing illness and death. In the United States, suboptimal vaccine uptake in adolescents and young adults has been observed for meningococcal conjugate (MenACWY) and serogroup B meningococcal (MenB) vaccines, particularly among marginalized communities, despite current recommendations by the Advisory Committee on Immunization Practices. A systematic literature search was conducted in the MEDLINE and MEDLINE In-Process, Embase, Cochrane, PsychInfo, and CINAHL databases to identify both drivers of, and barriers to, MenACWY and MenB vaccine uptake in adolescents and young adults. A total of 34 of 46 eligible studies that presented outcomes stratified by race/ethnicity, geography, and socioeconomic status were selected for review. Results showed MenACWY and MenB vaccination coverage in adolescents and young adults is impacted by racial/ethnic, socioeconomic, and geographic disparities. Gaps also exist in insurance for, or access to, these vaccines in adolescents and young adults. Moreover, there was variability in the understanding and implementation of the shared decision-making recommendations for the MenB vaccine. Disease awareness campaigns, increased clarity in accessing all meningococcal vaccines, and further research on the relationships between measures of marginalization and its impact on vaccine coverage in adolescents and young adults are needed to reduce the incidence of severe infections.

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Meningokokken-Impfung

Dornbusch,

Förster,

Prieler

et al. 2024

Paediatr. Paedolog.

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ZusammenfassungIn Österreich sind Meningokokken-Impfungen für unterschiedliche Altersgruppen empfohlen, jedoch wird nur jene gegen die Serogruppen ACWY im Jugendalter erstattet. Vor diesem Hintergrund stagnieren die Durchimpfungsraten – insbesondere bei Kindern aus einkommensschwachen Familien. Dies entspricht einer sozialen und ökonomischen Ungleichheit, welche für die betroffenen Familien und ihre behandelnden Ärzte eine große Belastung darstellt. Auf Basis einer Analyse der rezenten Meningokokken-Epidemiologie, von Impfempfehlungen, Impfprogrammen und sozioökonomischen Aspekten werden Hürden für eine Erweiterung des kostenfreien Impfprogramms gegen Meningokokken definiert und Maßnahmen vorgeschlagen, die einen umfassenden Impfschutz gegen invasive Meningokokkenerkrankungen (IME) gewährleisten könnten. Die Aufnahme aller Impfungen gegen Meningokokken ins kostenfreie Kinderimpfprogramm würde die Durchimpfungsrate gegen diese schwere Infektionskrankheit mit großer Wahrscheinlichkeit erhöhen und die tägliche Arbeit von Pädiatern und Allgemeinmedizinern hinsichtlich der erforderlichen Impfaufklärungsgespräche maßgeblich erleichtern.

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Equity in vaccination policies to overcome social deprivation as a risk factor for invasive meningococcal disease

Cited by 24 publications

References 95 publications

Societal Preferences for Meningococcal B Vaccination in Children: A Discrete Choice Experiment in Spain

Societal Preferences for Meningococcal B Vaccination in Children: A Discrete Choice Experiment in Spain

The Impact of Social Determinants of Health on Meningococcal Vaccination Awareness, Delivery, and Coverage in Adolescents and Young Adults in the United States: A Systematic Review

Meningokokken-Impfung

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