As an essential load of the concrete dam, the abnormal change of uplift pressure directly threatens the safety and stability of the concrete dam. Therefore, it is of great significance to accurately and efficiently excavate the hidden information of the uplift pressure monitoring data to clarify the safety state of the concrete dam. Therefore, in this paper, density-based spatial clustering of applications with noise (DBSCAN) method is used to intelligently identify the abnormal occurrence point and abnormal stable stage in the monitoring data. Then, an application method of measured uplift pressure is put forward to accurately reflect the spatial distribution and abnormal position of uplift pressure in the dam foundation. It is easy to calculate and connect with the finite element method through self-written software. Finally, the measured uplift pressure is applied to the finite element model of the concrete dam. By comparing the structural behavior of the concrete dam under the design and measured uplift pressure, the influence of abnormal uplift pressure on the safety state of the concrete dam is clarified, which can guide the project operation. Taking a 98.5 m concrete arch dam in western China as an example, the above analysis ideas and calculation methods have been verified. The abnormal identification method and uplift pressure applying method can provide ideas and tools for the structural diagnosis of a concrete dam.