Eranthemoside, a new iridoid glucoside from Eranthemum pulchellum (Acanthaceae)

UPLC-MS/MS-based molecular networking and NMR structural determination for the untargeted phytochemical characterization of the fruit of Crescentia cujete (Bignoniaceae)

“…In the HMBC spectrum, correlations of proton signal of two germinal oxy-methylene groups ascribed at H-10 (δH 3.73, d, J = 11.4 Hz and 3.61, d, J = 11.4 Hz) to C-7, C-8 and C9, indicated the connection of C-10 to C-8. Based on the above information, compound 13 was assumed to be an iridoid glycoside, similar to eranthemoside previously isolated from Eranthemum pulchellum (Fischer et al, 1987). A well-known effect for the configuration of C-8 epimers previously observed in the 13 C NMR data of gardenoside and monotropein methyl ester (Chaudhuri et al, 1980) was evidenced by compound 13 and eranthemoside.…”

“…A well-known effect for the configuration of C-8 epimers previously observed in the 13 C NMR data of gardenoside and monotropein methyl ester (Chaudhuri et al, 1980) was evidenced by compound 13 and eranthemoside. The β-oriented OH group at C-8 in compound 13 was determined from the comparison of its 13 C NMR data with those reported for eranthemoside (Fischer et al, 1987;Kanchanapoom et al, 2004). It was observed that an 8β-hydroxy substituent in compound 13 exerts a deshielding effect of ~7 ppm to C-9 in respect to eranthemoside (Chaudhuri et al, 1980).…”

“…Based on the above evidence, the structure of 13 was determined to be 8-epi-eranthemoside. Finally, epi-eranthemoside, similar to eranthemoside (Fischer et al, 1987), appears to be unstable and turns brownish a few days after its purification.…”

Macro- And Micromorphological Study of the Leaf, Stem and Inflorescence of Eranthemum Nervosum T. Anders (Fam. Acanthaceae), Cultivated in Egypt

“…On reviewing current literature no pharmacological study for this plant could be traced. Chemical investtigation of this plant identified one iridoid (Eranthemoside) 6 and one alkaloid (3-Methoxy vasicinone) 7 .…”

Phytochemical and Biological Study of Eranthemum Nervosum (Vahl) R. Br., Cultivated in Egypt

“…Eranthemum nervosum (E. pulchellum) 4 , cultivated in Egypt is one of these ornamentals. On reviewing current literature, no biological study for this plant could be traced while chemical investigation led to isolation of one iridoid (eranthemoside) 5 and one alkaloid (3methoxy vasicinone) 6 . The present study is dealing with the isolation and identification of the chemical constituents in addition to the biological activities of the aerial parts of this plant.…”