Erectile Dysfunction

Sexual function and ageing

“…[12] In the USA, testosterone use has increased five-fold from 2000 to 2011, with almost 5.3 million men using it. [14] In men with established coronary artery disease using testosterone, the absolute risk of rehospitalisation, death, myocardial infarction and stroke showed an increase of 5.8% over 3 years. [15] While multiple medical risk factors are associated with erectile dysfunction (ED), age is the greatest risk factor.…”

“…ED is found in 20 -40% of men aged 60 -69 years and increases to 50 -100% in men over 70. [14] Sildenafil, vardenafil and tadalafil are all phosphodiesterase type-5 inhibitors (PDE5-Is) registered for the treatment of ED. [14] They are effective in reducing ED by up to 65% and associated with no increase in myocardial infarction or death, cardiac ischaemia or cardiac haemodynamics on exercise testing.…”

“…[14] Sildenafil, vardenafil and tadalafil are all phosphodiesterase type-5 inhibitors (PDE5-Is) registered for the treatment of ED. [14] They are effective in reducing ED by up to 65% and associated with no increase in myocardial infarction or death, cardiac ischaemia or cardiac haemodynamics on exercise testing. [14] They are contraindicated with the concomitant use of nitrates, which may result in severe hypotension.…”

“…[14] They are effective in reducing ED by up to 65% and associated with no increase in myocardial infarction or death, cardiac ischaemia or cardiac haemodynamics on exercise testing. [14] They are contraindicated with the concomitant use of nitrates, which may result in severe hypotension. [14] Testosterone supplementation together with PDE5-Is is successful in men ≥65 years who have low testosterone concentrations and who are initially unresponsive to PDE5-Is.…”

“…[14] They are contraindicated with the concomitant use of nitrates, which may result in severe hypotension. [14] Testosterone supplementation together with PDE5-Is is successful in men ≥65 years who have low testosterone concentrations and who are initially unresponsive to PDE5-Is. [14] …”