Erectile dysfunction in male heroin users, receiving methadone and buprenorphine maintenance treatment

Quaglio, Gianluca; Lugoboni, Fabio; Pattaro, Cristian; Melara, Barbara; Mezzelani, Paolo; Jarlais, Don C. Des

doi:10.1016/j.drugalcdep.2007.09.025

Cited by 77 publications

(100 citation statements)

References 28 publications

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“…The causal relationship between depression and erectile dysfunction is probably bidirectional. The depression may be a consequence of erectile dysfunction or depression may cause erectile dysfunction (Seidman and Roose, 2000;Quaglio et al, 2008). Past studies showed that data regarding depression and erectile dysfunction are inconsistent.…”

Section: Discussionmentioning

confidence: 99%

Depression in male patients on methadone maintenance therapy

Baharudin

Mislan²,

Ibrahim

et al. 2013

Asia-Pacific Psychiatry

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Introduction: Depression is one of the most common psychiatric conditions in men. The aim of the study was to determine the depressive symptoms and associated factors among men on methadone maintenance therapy (MMT). Methods: A cross-sectional study was conducted involving 108 subjects who attended the Drug Clinic at Hospital Kuala Lumpur. The instruments used include the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition Axis-I Disorder, Beck Depression Inventory and the 15-item International Index of Erectile Function. Results: The rate of depression was 44.4%. There were significant associations between Malay ethnicity, secondary education level and concurrent illicit cannabis use with depression (P < 0.05). However, there was no significant associations between depression and erectile dysfunction (P = 0.379). Discussion: Even though depression is common among men on MMT, it is often missed by the treating doctors. It is important to make the treating doctors aware that depression is a serious clinical condition that has a profound impact on the individual and compliance to treatment.

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Section: Discussionmentioning

confidence: 99%

Depression in male patients on methadone maintenance therapy

Baharudin

Mislan²,

Ibrahim

et al. 2013

Asia-Pacific Psychiatry

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“…= 6.3) younger than the index subjects, 68% of the partners were employed, 40% had no more than 8 years of education, and 14% of the partners had used heroin. In the study of Quaglio et al (2008), very substantial rates of ED were found: 19%of the patients reported severe ED and another 23%reported mild to moderate ED.…”

Section: Erectile Dysfunctionsmentioning

confidence: 99%

“…However, the age of the subjects in this study ranged from 18 to 47, with a mean age of 31 where 42% reported ED, while in a general population study of more than 2000 Italian males, only 2% in the age group 18-39 reported ED. In a study by Quaglio et al (2008), the univariate analysis showed a significant association between treatment and ED, with buprenorphine patients reporting less ED than methadone patients, but this was not confirmed by the multivariate analysis. Quaglio et al (2008) did not find any significant association between either methadone dose or buprenorphine dose and ED, or with reported duration of either methadone or buprenorphine treatment and ED.…”

Section: Erectile Dysfunctionsmentioning

confidence: 99%

“…The majority of previous studies of ED among drug users have used nonvalidated questionnaires, so caution should be exercised when comparing these earlier study findings to the present results. Nevertheless, all the surveys by Quaglio et al (2008) indicate high rates of ED among methadone/buprenorphine patients. However, the age of the subjects in this study ranged from 18 to 47, with a mean age of 31 where 42% reported ED, while in a general population study of more than 2000 Italian males, only 2% in the age group 18-39 reported ED.…”

Section: Erectile Dysfunctionsmentioning

confidence: 99%

“…Moreover, in the general population, endocrinal causes are responsible only in a small number of cases of ED (Brown & Zueldorff, 2007). A study by Quaglio et al (2008) included 201 males; subjects were 18-47 years old (mean = 31, S.D. = 6.0).…”

Section: Erectile Dysfunctionsmentioning

confidence: 99%

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Maintenance Therapy and Sexual Behavior

Giacomuzzi¹,

Garber²,

Farneti³

et al. 2011

Sexual Dysfunctions - Special Issues

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Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment

Chang,

Huang,

Fang

et al. 2023

Neuropsychopharm Rep

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AimAlthough studies in Western countries have investigated the quality of life (QoL) of heroin users, limited research on this topic has been conducted in Asia. The present study assessed QoL in patients with heroin dependence receiving medications to treat opioid use disorder.MethodsWe performed a cross‐sectional study of patients with heroin dependence receiving methadone and buprenorphine treatment. The demographic and substance use variables of patients receiving methadone and buprenorphine were compared. The Chinese Health Questionnaire (CHQ‐12), Obsessive Compulsive Drug Use Scale (OCDUS), and World Health Organization Quality of Life Short Form Taiwan version (WHOQOL‐BREF‐T) were administered to measure patient mental health problems, addiction severity, and QoL, respectively. Multivariate regression was used to identify the factors associated with QoL.ResultsA total of 149 patients receiving methadone and 31 receiving buprenorphine completed the questionnaires. Individuals in the buprenorphine group were more likely to be married (p = 0.024) or employed (p = 0.024), have a higher educational level (p = 0.013), have lower drug craving (OCDUS: p = 0.035), or have higher QoL (WHOQOL‐BREF‐T: p = 0.004) than those in the methadone group. After adjustment for other variables, employment was positively associated with the physical, psychological, and environmental domains of QoL. Receiving buprenorphine treatment (p = 0.032) and longer treatment duration (p = 0.016) were associated with higher psychological QoL.ConclusionSeveral factors were associated with QoL in patients with heroin dependence. Some measures may improve their QoL, such as reducing employment barriers, improving treatment adherence, or increasing accessibility to buprenorphine treatment.

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Erectile dysfunction in male heroin users, receiving methadone and buprenorphine maintenance treatment

Cited by 77 publications

References 28 publications

Depression in male patients on methadone maintenance therapy

Depression in male patients on methadone maintenance therapy

Maintenance Therapy and Sexual Behavior

Quality of life and associated factors of heroin‐dependent patients receiving methadone and buprenorphine maintenance treatment

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