Erectile dysfunction in patients with chronic renal failure

Abstract

Objective: Determine the prevalence of erectile dysfunction in patients undergoing hemodialysis. Materials and Methods:This cross-sectional study was carried out to determine the prevalence of erectile dysfunction in a population of 58 patients in hemodialysis program. Erectile dysfunction was assessed by using the International Index of Erectile Function (IIEF). Information on demographic data, renal failure, comorbidities, laboratory tests and search for medical treatment for erectile dysfunction by means of interviews and researches in medical charts was obtained. Student t test was utilized to compare the laboratory results between group of patients with and without erectile dysfunction. The chi-square test was utilized to compare the comorbidities and the characteristics of the population studied between the groups of patients with and without erectile dysfunction. The significance level considered was 5%. Results: Mean patient age was 50.2 ± 14.6 years and the time of hemodialysis was 30.4 ± 28.4 months. The prevalence of erectile dysfunction was 60.3%. A progressive increase respecting the age was reported. In patients younger than 50 years, this prevalence reached 31.4% and in patients older than 50 years, this prevalence reached 68.6%. With respect to the comorbidities, hypertensive patients prevailed with 94.8% of the total, whilst diabetic patients represented 24.9%. However only the association between diabetes and erectile dysfunction was significant. Patients with erectile dysfunction presented significantly lower values for serum creatinine and Kt/V. There was no variation between the groups with reference to calcium, potassium, phosphorus, hematocrit, hemoglobin, pre-and post-dialysis urea values. There was no correlation between erectile dysfunction and time of dialysis. Amongst patients with erectile dysfunction, 8.6% sought medical care. Conclusions: The prevalence of erectile dysfunction in patients in hemodialysis program was of 60.3%. Age, diabetes and hemodialysis characteristics are associated to higher incidence of erectile dysfunction.

Erectile Dysfunction in Chronic Hemodialysis Patients in Dakar: a Cross-Sectional Study in 2012

“…The incidence is even higher in patients on chronic dialysis due to specific (5) and 83% in Saudi Arabia (6). Lower prevalence of ED has been reported in patients on dialysis living in Spain (7), Brazil (8), and Netherlands (9) (respectively 60%, 54.9%, and 69%). CIGOP in 1981 showed that more than 50% of male patients with CKD showed erectile dysfunction (10) The mild and moderate grades of ED, with a prevalence of respectively 28.8% and 27.4%, were the most represented severities in our patients.…”

“…In patients with ED, four grades of severity were defined as follows: mild (score, 17-21); light (score, 12-16); moderate (score, [8][9][10][11]; and severe (score, 5-7)…”

Determinants of Erectile Dysfunction in Hemodialysis Patients in CNHU-HKM, Cotonou

“…This assumption was confirmed by the results of kidney transplants in early stage of CKD which seem to improve erectile dysfunction [31]. Yet, Messina et al, Ajina et al and Malekmakan et al reported no correlation between hemodialysis duration and the onset of erectile dysfunction [7,8,28].…”

“…However, the low ED prevalence reported by Zbiti et al could be attributable to the young age of the study population (mean age = 45 ± 11.8 years) and the difference in methodology. [1,4,7,[20][21][22]27,29]. In fact, aging is a risk factor for occurrence of atherosclerosis.…”

“…The frequency of these sexual disorders is amplified in CKD patients among whom it is estimated between 50% and 70%, depending on the stage of kidney disease [4,6,7]. Half of end-stage CKD patients suffer from sexual disorders with reduced libido in association with impaired spermatogenesis [8].…”