Erectile dysfunction through the ages

Shah, Jyoti

doi:10.1046/j.1464-410x.2002.02911.x

Cited by 52 publications

(40 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a review by Shah, different civilizations' thoughts and reactions concerning this goal is eloquently discussed. 1 For example, poems from the Hindu civilization dating back 3000 to 4000 years are the earliest recordings of the human eternal search for substances that can enhance sexual experiences lead to the much unknown, "supersex," and/or treat erectile dysfunction (ED). 2 The ancient Egyptians had their share of aphrodisiacs with several papyri describing many medications for ED, including local penile application of oiled baby crocodile hearts, and ingestion of pine, salt, and watermelon.…”

Section: Introductionmentioning

confidence: 99%

Drug Addiction and Sexual Dysfunction

Zaazaa¹,

Bella²,

Shamloul³

2013

Endocrinology and Metabolism Clinics of North America

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Drug Addiction and Sexual Dysfunction

Zaazaa¹,

Bella²,

Shamloul³

2013

Endocrinology and Metabolism Clinics of North America

View full text Add to dashboard Cite

“…Sexual dysfunction is a condition that affects 15-30 million men worldwide, and it occurs in 10%-52% of men and 25%-63% of women (11,12). Many believe that sexual dysfunction is associated with the modern lifestyle.…”

mentioning

confidence: 99%

Toxic potentials of ten herbs commonly used for aphrodisiac effect in Turkey

Asadi¹,

Nath²,

Özhan³

2015

Turk J Med Sci

View full text Add to dashboard Cite

IntroductionSince ancient times, herbs have played an important role in the treatment of different diseases in many regions of world, largely for their expectorant, aphrodisiac, diuretic, diaphoretic, antispasmodic, stomachic, and sedative properties (1). The World Health Organization reported that 70%-80% of the global population relies on herbs for primary health care. In addition, because they are natural products, it is generally believed that herbs are essentially safe and free from side effects. Consequently, the consumption of nonprescription herbs has steadily increased over the past few decades (2).Despite the therapeutic advantages of herbs, reports have indicated the potential toxicity of some herbal components. Herbs contain a variety of chemical substances that act upon the body. In addition, the quality of herbs can be affected by toxic contaminants originating from industry, agriculture, and private households, including toxins that can cause mutagenic and carcinogenic effects from long-term and widespread use (3-6). Moreover, herbal medicines are generally a mixture of a number of herbs in a single preparation and contain several active ingredients that induce various pharmacological effects (7,8). To date, there are few scientific studies on the safety and potential toxicity of herbs, despite growing concerns over the lack of both scientific evidence and quality control data regarding the safety and efficacy of herbs (9,10).Sexual dysfunction is a condition that affects 15-30 million men worldwide, and it occurs in 10%-52% of men and 25%-63% of women (11,12). Many believe that sexual dysfunction is associated with the modern lifestyle. As a result, individuals turn to natural products, such as traditional herbs, that produce aphrodisiac effects for sexual enhancement. Aphrodisiac herbs are used to treat sexual dysfunction because they alter specific neurotransmitters or sex hormones. Specifically, herbs with aphrodisiac properties can induce vasodilatation that results in a sustained erection, and can cause irritation of genital mucosa that enhances sensory experience during coitus (13).Background/aim: Sexual dysfunction is a serious problem worldwide. In Turkey, herbal products are used by some people suffering from sexual dysfunction. Despite their therapeutic advantages, some constituents of herbs are potentially toxic and pose health risks because they can be bought from the market without a prescription. Therefore, we aimed to determine the safety of herbs possessing aphrodisiac effects, chosen on the basis of their frequency of medicinal use and commercial importance in Turkey. Materials and methods:Ten herbs (Anethum graveolens, Carthamus tinctorius, Citrus aurantium, Cocos nucifera, Glycyrrhiza glabra, Melissa officinalis, Nigella arvensis, Pinus pinea, Prunus mahaleb, and Zingiber officinale) were extracted with water, methanol, and chloroform. The cyto-and genotoxic potentials of the extracts were assessed using an MTT test on a rat kidney cell line and an Ames assay in Salmonella typhi...

show abstract

“…Recent reports strengthen the perspective that oxidative stress is increased in diabetes resulting in production of free radicals and reactive oxygen species (ROS) causing impaired sexual function (Shah, 2002;. Sexual dysfunction is experienced by males suffering from diabetes mellitus at a greater frequency than by the general population across all ages.…”

Section: Introductionmentioning

confidence: 90%