Erfahrungen an 89 Colitis-ulcerosa-Fällen der Abteilung Boiler im Allgemeinen Krankenhaus Wien

The Epidemiology of IBD

“…In the case of ulcerative colitis, this is not a new observation. Since the first report from Australia in the 1950s, 14 there has been an abundance of studies showing ulcerative colitis as a protective factor and, sometimes, former smoking being associated with an increased risk. 15 The underlying biologic mechanism still remains unknown but for Crohn's disease, there is a reasonable biologic model for an increased risk if one assumes that part of the disease process is a multifocal gastrointestinal infarction, which could be aggravated by cigarette smoke.…”

Epidemiology of Inflammatory Bowel Disease

“…As long ago as the 1950s, Boller [17] made the observation that smoking was less prevalent among patients with ulcerative colitis than among other patient groups. This observation has since been confirmed in many studies [18].…”