Erosion and abrasion-inhibiting in situ effect of the Euclea natalensis plant of African regions

Abstract

Erosion and abrasion-inhibiting in situ effect of the Euclea natalensis plant of African regionsAbstract: This study evaluated the effect of Euclea natalensis gel on the reduction of erosive wear with or without abrasion, in enamel and dentin. During two five-day experimental crossover phases, volunteers (n = 10) wore palatal devices containing human enamel and dentin blocks (E = 8 and D = 8). The gel was applied in a thin layer in the experimental group, and was not applied in the control group. In the intraoral phase, volunteers used the palatal appliance for 12 h before the gel treatment, and were instructed to start the erosive challenges 6 h after the gel application. Erosion was performed with Coca-Cola ® (for 5 min) 4 times/day. The appliance was then put back into the mouth and was brushed after 30 minutes. After intraoral exposure, the appliances were removed and the specimens were analyzed using profilometry (mean ± SD, μm). The Euclea natalensis gel caused less wear in enamel in the experimental group (EROS = 12.86 ± 1.75 µm; EROS + ABRAS = 12.13 ± 2.12 µm) than in the control group (EROS = 14.12 ± 7.66 µm; EROS + ABRAS = 16.29 ± 10.72 µm); however, the groups did not differ from each other significantly. A statistically significant value was found for erosion and eros + abrasion in dentin (p = 0.001). Euclea natalensis may play a role in the prevention of dentin loss under mild erosive and abrasive conditions. A clinical trial is required to confirm these promising results in a clinical situation.

Protective effect of green tea catechins on eroded human dentin: an in vitro/in situ study

“…The sample size was selected according to the data obtained from a previous study. 28 As a result, 20 healthy adult volunteers, ranging from 20 to 32 years old, were recruited. Visual and tactile clinical examination was carried out to select volunteers with teeth that were caries-free as per the International Caries Detection and Assessment System (ICDAS), 29 and free of dental wear as per the Basic Erosive Wear Examination (BEWE) index.…”

Review of Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of Euclea natalensis A.DC.

“…Extracts from Euclea natalensis possess a wide spectrum of pharmacological properties, including antibacterial [ 25 , 35 , 40 , 50 , 52 , 61 , 62 , 63 ], antimycobacterial [ 17 , 39 , 52 , 54 , 55 , 64 , 65 , 66 , 67 , 68 , 69 , 70 ], antifungal [ 51 , 57 ], antiviral [ 18 , 71 ], antidiabetic [ 72 ], antioxidant [ 67 , 72 ], antiplasmodial [ 73 ], larvicidal [ 74 ], antischistosomal [ 75 ], molluscicidal [ 76 ], dentin permeability [ 77 , 78 ], hepatoprotective [ 79 ], cytotoxicity [ 17 , 18 , 35 , 67 , 80 ] and toxicity [ 19 ] activities as outlined below. Some of the documented pharmacological properties of crude extracts and compounds isolated from the species may be responsible for the ethnomedicinal uses of the species indicated in Table 1 .…”

“…This effect can be attributed to the naphthoquinone compounds present in twigs and roots of E. natalensis as the compounds result in the dentin tubule obliteration due to the formation of a protective layer on the teeth [ 77 ]. Similarly, Sales-Peres et al [ 78 ] evaluated the effect of E. natalensis gel on the reduction of erosive wear with or without abrasion, in enamel and dentin. The authors carried out five-day experimental crossover phases with volunteers wearing palatal devices containing human enamel and dentin blocks.…”

“…The E. natalensis gel caused less wear in enamel in the experimental group than in the control group and a statistically significant value was found for erosion and erosion and abrasion in dentin. Therefore, E. natalensis may play a role in the prevention of dentin loss under mild erosive and abrasive conditions [ 78 ]. Based on the research findings of Sales-Peres et al [ 77 , 78 ], E. natalensis extracts may be an alternative health product to protect oral health and prevent dental caries, tooth wear and dentinal sensitivity.…”

“…Therefore, E. natalensis may play a role in the prevention of dentin loss under mild erosive and abrasive conditions [ 78 ]. Based on the research findings of Sales-Peres et al [ 77 , 78 ], E. natalensis extracts may be an alternative health product to protect oral health and prevent dental caries, tooth wear and dentinal sensitivity. These findings support the traditional use of the twigs and roots of E. natalensis as chewing sticks, toothbrush, mouthwash and remedy for toothache in Kenya [ 5 , 30 ], Mozambique [ 34 , 35 ], South Africa [ 4 , 8 , 13 , 35 , 38 ], Swaziland [ 32 ] and Tanzania [ 5 , 7 , 21 ].…”