Erosive adenomatosis of the nipple in a man

Abstract

Letters to the EditorBlaschkoid hypermelanosis probably fit somewhere in the clinical spectrum of zosteriform and naevoid whorled hypermelanoses, and cannot be exactly designated using the available terminology. Older terms like linear and whorled nevoid hypermelanosis and progressive cribriform and zosteriform hyperpigmentation do not sufficiently encompass the entire range of clinical manifestations and lead to a lot of misunderstanding regarding these mosaic pigmentary disorders. These confusing terms should be discarded; a revised nomenclature and classification of these pigmentary anomalies is the need of the hour.

Nipple adenoma in a female patient presenting with persistent erythema of the right nipple skin: case report, review of the literature, clinical implications, and relevancy to health care providers who evaluate and treat patients with dermatologic conditions of the breast skin

“…NA most typically presents in women in their 4th and 5th decades of life [ 26 , 52 ]. However, it has also been reported in men [ 2 , 12 , 14 , 20 , 31 , 44 , 90 , 96 , 104 , 107 , 112 , 123 ], as well as throughout childhood [ 86 , 99 , 106 ]. While most cases of NA are unilateral, there have been rare reports of bilateral disease [ 22 , 28 ].…”

Surgical management of erosive adenomatosis of the nipple: A case report

“…Fortunately, it is most often found in women during the fifth decade. However, a few cases have been described in children [3] and even in men [6] . Our patient was 45; and, to the best of our knowledge, this is one of the very few cases described in black women from sub-Saharan Africa.…”

<p>Erosive Adenomatosis of the Nipple: A Clinical Diagnostic Challenge</p>

“… 1 – 3 EAN occurs in middle-aged women, typically in fourth and fifth decades of life, and extremely less in men and children. 1 , 4 The tumor is usually unilateral and asymptomatic, and the common clinical symptoms are erosion, serous discharge (serous and/or sanguineous), nodularity, swelling, itching and erythema of the nipple. 1 , 2 , 4 Physical examination often reveals an irregular ulcer on the nipple without breast lump or lymphadenopathy.…”

“… 1 , 2 , 4 Physical examination often reveals an irregular ulcer on the nipple without breast lump or lymphadenopathy. 1 , 4 …”

“…The major histopathology of EAN is characterized by a proliferation of lactiferous ducts, and gland-like structures in the stroma with clear border. 1 , 4 In the ducts, two types of epithelial cells consisted by luminal epithelial and myoepithelial cells can be found, 1 , 5 this is important to distinguish EAN from invasive breast carcinoma. 6 Tumor may grow into the epidermis and replace squamous epithelium, or push the papillomatous lesion to the surface of the nipple, which make it look like an erosion or ulceration.…”