Erosive pustular dermatosis (chronic atrophic dermatosis of the scalp and extremities)

Semkova, Kristina; Tchernev, Georgi; Wollina, Uwe

doi:10.2147/ccid.s47019

Cited by 13 publications

(24 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Here, we present 3 cases of EPD isolated to the face and occurring after ablative resurfacing procedures. We suspect that similar cases have occurred but remain undiagnosed or unreported, 6 including 2 cases of "delayed healing without a known cause" after full-face ablative laser resurfacing. 7 Weeks to months after initial postoperative healing, our patients developed erosions, crusting, and brightly erythematous patches in previously resurfaced areas, especially the forehead and lateral cheeks.…”

Section: Discussionmentioning

confidence: 99%

Facial Erosive Pustular Dermatosis After Cosmetic Resurfacing

et al. 2017

View full text Add to dashboard Cite

rosive pustular dermatosis (EPD) is characterized by itchy or painful erythematous plaques with erosions, sterile pustules, and yellow crusts. The etiology of EPD is unknown as laboratory tests, microbiological cultures, and histopathological studies are nondiagnostic. Cuts and bruises, cryotherapy, and other trauma to actinically damaged skin, usually a bald scalp, are inciting factors. [1][2][3][4] Here, we present 3 cases of facial EPD occurring after cosmetic resurfacing procedures. We evaluated these cases between between September 10, 2010, and May 6, 2016.

show abstract

Section: Discussionmentioning

confidence: 99%

Facial Erosive Pustular Dermatosis After Cosmetic Resurfacing

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Recurrent erosions and yellow to brown crusts and pustules over time result in scarring and subsequent alopecia, telangiectasia, and atrophy of the skin [2]. The hyperkeratotic lesions are not painful and pruritus is rare [3]. Triggers have been reported to include imiquimod [4], ingenol mebutate [5], and herpes zoster [6].…”

Section: Answermentioning

confidence: 99%

“…The response to corticosteroids by EPDS suggests immunological dysfunction may be related to the pathomechanism, and the response to corticosteroids can aid in diagnosis [7]. Among the most common causes of EPDS are lacerations, bruises, shingles, severe sunburns that result in blistering, surgical resections, skin grafting, topical chemotherapy, and cryotherapy, yet EPDS persists long after the initial insult [3]. Autoimmune diseases also have been reported in association with EPDS such as rheumatoid arthritis [7].…”

Section: Answermentioning

confidence: 99%

See 1 more Smart Citation

Chronic Crusted Scalp Lesion of an Elderly Male

Gamret

Fertig

Darwin

et al. 2017

Skin Appendage Disord

View full text Add to dashboard Cite

“…Curettage debridement with electrodesiccation has also been reported to be beneficial in some cases. 4…”

mentioning

confidence: 99%

Erosive Pustular Dermatosis of the Scalp

2019

View full text Add to dashboard Cite

An adult man presented with a localized pustular eruption on the scalp (Figure). He complained of pain and burning at the site. Prior to the onset of the lesions, he had undergone surgery for the removal of a large squamous cell carcinoma on the scalp. The defect was covered with a skin graft. Three months after the surgery, he developed a pustular eruption on the graft. He was initially treated for several months with topical antibiotics and bland dressings, with no improvement.Physical examination revealed a localized eruption consisting of erosions and nonfollicular confluent pustules, covered by yellowbrown keratotic crusts, alternating with atrophic areas. Bacterial cultures of several pustules were sterile, and the biopsy showed nonspecific inflammatory reaction. Based on the history of recent surgery, the clinical appearance, the negative cultures, and the nonspecific biopsy, the diagnosis of erosive pustular dermatosis of the scalp (EPDS) was established. The patient was started on topical corticosteroid treatment followed by significant improvement of the lesions within 2 weeks.An inflammatory dermatosis, EPDS was first described in the late 1970s by Burton 1 and Pye et al. 2 It usually affects elderly patients with atrophic sun-damaged skin, often with coexistent or previously treated actinic keratoses and/or invasive squamous or basal cell carcinoma. Local trauma and surgery, skin infections such as herpes zoster, and topical treatments like imiquimod may also trigger the disease. Patients present with yellow-brown crusts, erosions, pustules, and lakes of pus on the scalp. The end result is scarring alopecia, which is secondary to chronic inflammation with subsequent destruction of the hair follicle. 3 Since EPDS is a clinical diagnosis, microbial, histologic, and immunofluorescence studies may be necessary to exclude cutaneous infections, pemphigus foliaceous, nonmelanoma skin cancer, and folliculitis decalvans. Characterized by chronic, ongoing inflammation, EPDS might require long-term management. Current recommendations suggest as a first-line therapy high-potency topical corticosteroids or topical calcineurin inhibitors (tacrolimus). Secondline therapies include oral corticosteroids, topical calcipotriol, oral acitretin, and dapsone gel. Curettage debridement with electrodesiccation has also been reported to be beneficial in some cases. 4

show abstract

Erosive pustular dermatosis (chronic atrophic dermatosis of the scalp and extremities)

Cited by 13 publications

References 34 publications

Facial Erosive Pustular Dermatosis After Cosmetic Resurfacing

Facial Erosive Pustular Dermatosis After Cosmetic Resurfacing

Chronic Crusted Scalp Lesion of an Elderly Male

Erosive Pustular Dermatosis of the Scalp

Contact Info

Product

Resources

About