ERPs obtained with the auditory oddball paradigm in coma and altered states of consciousness: clinical relationships, prognostic value, and origin of components

Guérit, Jean‐Michel; Verougstraete, Donatienne; Tourtchaninoff, Marianne de; Debatisse, D.; Witdoeckt, Catherine

doi:10.1016/s1388-2457(99)00061-9

Cited by 67 publications

(27 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A much larger study of 128 patients, but using only a single recording, by Fischer et al [1999] failed to confirm these findings, MMN (duration shift paradigm: 86% 75-ms and 14% 30-ms 800-Hz tones, stimulus rate of F1.5/s) providing low sensitivity (31.6%) in predicting return of consciousness, although a high specificity when seen together with an N 100 component (90.9%). A similar frontocentral negative auditory ERP component (frequency shift paradigm: 85% 750-Hz and 15% 1000-Hz tones, stimulus rate of 0.7/s), albeit much later (mean latency of 330 ms), has been recorded in a group of 83 comatose patients by Guerit et al [1999]. Presence of this later negative response predicted a 'good outcome' with a sensitivity of 72.0% and specificity of 47.7%.…”

Section: Mmn In Coma and Persistent Unresponsivenessmentioning

confidence: 59%

Coma Outcome Prediction Using Event-Related Potentials: P<sub>3</sub> and Mismatch Negativity

Kane

Butler²,

Simpson

2000

Audiol Neurotol

View full text Add to dashboard Cite

The prediction of the outcome from coma is of considerable importance to the patients, their relatives and attendant medical staff, and yet current clinical methods lack sensitivity and specificity. Objective investigations can enhance the accuracy of such predictions and are an important adjuvant when reaching decisions to continue or terminate life support. Of the neurophysiological methods available, electroencephalography and short-latency somatosensory evoked potentials have proved the most useful in the clinical setting. These tests are good predictors of an adverse outcome; however, they tell us only about the ongoing cerebral activity and integrity of the primary somatosensory pathways, respectively. The presence of long-latency event-related potentials has been shown to be a useful predictor of a favourable neurological outcome, and thus their use complements other neurophysiological techniques. Their potential application in clinical practice is reviewed.

show abstract

Section: Mmn In Coma and Persistent Unresponsivenessmentioning

confidence: 59%

Coma Outcome Prediction Using Event-Related Potentials: P<sub>3</sub> and Mismatch Negativity

Kane

Butler²,

Simpson

2000

Audiol Neurotol

View full text Add to dashboard Cite

show abstract

“…Stimulus duration was 50 ms, linear rise/fall time was 5 ms, intensity was 70 dB , and ISI was 850 ms. This paradigm was designed to detect the early auditory cortical responses expressed in components N100 (defined as the most negative deflection within 50 to 200 ms post onset of a tone; Näätänen and Picton, 1987), and P200 (most positive deflection between 100 and 250; Crowley and Colrain, 2004), and -as an indicator of deeper differentiation -the P300 (most positive deflection between 250 and 500 ms; Polich, 2007; in patients the interval was chosen between 300 and 700 ms, to compensate for the delayed latencies of cognitive ERPs in patients with acquired brain damage; Guérit et al, 1999). Tone streams were presented twice, once in a passive (always presented first) and once in an active condition.…”

Section: Methodsmentioning

confidence: 99%

Information processing in patients in vegetative and minimally conscious states

Real

Veser

Erlbeck

et al. 2016

Clinical Neurophysiology

View full text Add to dashboard Cite

“…However, if one wishes specifically to examine conscious processing, other components of the ERP might be more important. In the patient coming out of coma, these other potentials may also relate to prognosis [Gott et al, 1991;Guérit et al, 1999;Fischer et al, 1999;Kane et al, 2000].…”

Section: Disorders Of Consciousnessmentioning

confidence: 99%

Mismatch Negativity: Different Water in the Same River

Picton

Alain

Otten³

et al. 2000

Audiol Neurotol

539

364

View full text Add to dashboard Cite

The mismatch negativity (MMN) is a frontal negative deflection in the human event-related potential that typically occurs when a repeating auditory stimulus changes in some manner. The MMN can be elicited by many kinds of stimulus change, varying from simple changes in a single stimulus feature to abstract changes in the relationship between stimuli. The main intracerebral sources for the MMN are located in the auditory cortices of the temporal lobe. Since it occurs whether or not stimuli are being attended, the MMN represents an automatic cerebral process for detecting change. The MMN is clinically helpful in terms of demonstrating disordered sensory processing or disordered memory in groups of patients. Improvements in the techniques for measuring the MMN and in the paradigms for eliciting it will be needed before the MMN can become clinically useful as an objective measurement of such disorders in individual patients.

show abstract

ERPs obtained with the auditory oddball paradigm in coma and altered states of consciousness: clinical relationships, prognostic value, and origin of components

Cited by 67 publications

References 17 publications

Coma Outcome Prediction Using Event-Related Potentials: P<sub>3</sub> and Mismatch Negativity

Coma Outcome Prediction Using Event-Related Potentials: P<sub>3</sub> and Mismatch Negativity

Information processing in patients in vegetative and minimally conscious states

Mismatch Negativity: Different Water in the Same River

Contact Info

Product

Resources

About