Erratum

Kim, D; Gregory, CW; Smith, G. Jason; Mohler, J. L.

doi:10.1002/(sici)1097-0320(19990401)35:4<376::aid-cyto11>3.0.co;2-b

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Reduced Ncor2 Expression Accelerates Disease Progression In Vivo1

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2021

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“…Green fluorescent protein (GFP) detection of the shRNA constructs and reduced NCOR2 levels were confirmed at all stages of disease (Figures 2A and 2B; Figure S3C). Expression of androgen-regulated genes was acutely repressed by ADT but became reexpressed in recurrence concomitant with increased AR expression (Figure S3D) (Kim et al, 2002). Reduced NCOR2 expression did not impact the primary (Abida et al, 2019, Robinson et al, 2015a, Armenia et al, 2018, Taylor et al, 2010 (red), and neuroendocrine (Beltran et al, 2016) 4 Cell Reports 37, 110109, December 14, 2021…”

Section: Reduced Ncor2 Expression Accelerates Disease Progression In Vivomentioning

confidence: 99%

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

et al. 2021

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Section: Reduced Ncor2 Expression Accelerates Disease Progression In Vivomentioning

confidence: 99%

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

et al. 2021

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“…Tissue samples are obtained for diagnostic purposes, so normal tissues are taken adjacent to the tumor, and may result in contamination [47,49]. Surgical manipulation and devascularization, sample collection, freezing time, and archival storage methods may also differ, influencing results [24,48,[50][51].…”

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confidence: 99%

A Review of the Expression of Genes Involved in Sex Steroid Hormone Metabolism in Prostate Tissue: A Need for Epigenetic Information

Ritchey

2013

J. Anal. Oncol.

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There is strong clinical and laboratory evidence indicating that sex steroid hormones are important to the development and progression of prostate cancer, yet results from epidemiologic research conflicts. Examining gene expression in the sex steroid hormone pathway may uncover differences between cancerous and non-cancerous prostate tissues, yet our review using a pathway-oriented approach indicates that there is limited consistency across results, with the exception of GSTP1 found in the estrogen pathway, which was under-expressed in cancerous prostate tissue. This agrees with past studies that reported GSTP1 is methylated in prostate cancer. With new cost-effective technology, we can screen for epigenetic markers, like methylation, which can be applied in epidemiological studies. A clearer understanding of gene expression and epigenetic mechanisms in prostate cancer may contribute to improving prevention, diagnosis, and treatment.

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Erratum

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Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

A Review of the Expression of Genes Involved in Sex Steroid Hormone Metabolism in Prostate Tissue: A Need for Epigenetic Information

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