Erratum: Antibacterial Bioactive Glass, S53P4, for Chronic Bone Infections – A Multinational Study

Lindfors, Nina; Geurts, Jan; Drago, Lorenzo; Arts, Jacobus J.; Juutilainen, Vesa; Hyvönen, Pekka; Suda, Arnold J.; Aloj, Domenico; Artiaco, Stefano; Alizadeh, Chingiz; Brychcy, Adrian; Białecki, Jerzy; Romanò, Carlo Luca

doi:10.1007/5584_2017_13

Cited by 7 publications

(1 citation statement)

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“…Hence, to mimic a situation closer to the physiological environment, a recent study investigated the antimicrobial activity of bioactive glass S53P4 combined with an autologous bone graft [ 44 ], observing its ability to maintain good, though attenuated, in vitro antimicrobial activity in the presence of body fluids and tissues [ 44 ]. Although the antibacterial properties of bioactive glass due to the local pH increase have been extensively demonstrated in vitro, little evidence has been reported in an in vivo buffered system [ 45 ]. An additional factor contributing to antimicrobial properties is the release of silica, calcium, and phosphate ions, causing perturbations of the membrane potential of bacteria and determining a higher osmotic pressure [ 8 , 36 , 37 ].…”

Section: Antibacterial Activity Of Bioactive Glassmentioning

confidence: 99%

Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review

2018

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Bone defects caused by trauma or pathological events are major clinical and socioeconomic burdens. Thus, the efforts of regenerative medicine have been focused on the development of non-biodegradable materials resembling bone features. Consequently, the use of bioactive glass as a promising alternative to inert graft materials has been proposed. Bioactive glass is a synthetic silica-based material with excellent mechanical properties able to bond to the host bone tissue. Indeed, when immersed in physiological fluids, bioactive glass reacts, developing an apatite layer on the granule’s surface, playing a key role in the osteogenesis process. Moreover, the contact of bioactive glass with biological fluids results in the increase of osmotic pressure and pH due to the leaching of ions from granules’ surface, thus making the surrounding environment hostile to microbial growth. The bioactive glass antimicrobial activity is effective against a wide selection of aerobic and anaerobic bacteria, either in planktonic or sessile forms. Furthermore, bioglass is able to reduce pathogens’ biofilm production. For the aforementioned reasons, the use of bioactive glass might be a promising solution for the reconstruction of bone defects, as well as for the treatment and eradication of bone infections, characterized by bone necrosis and destruction of the bone structure.

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Section: Antibacterial Activity Of Bioactive Glassmentioning

confidence: 99%

Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review

2018

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Herbalism and glass-based materials in dentistry: review of the current state of the art

Singer,

Bourauel

2023

J Mater Sci: Mater Med

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Half a million different plant species are occurring worldwide, of which only 1% has been phytochemically considered. Thus, there is great potential for discovering novel bioactive compounds. In dentistry, herbal extracts have been used as antimicrobial agents, analgesics, and intracanal medicaments. Glass-ionomer cement (GIC) and bioactive glass (BAG) are attractive materials in dentistry due to their bioactivity, adhesion, and remineralisation capabilities. Thus, this review summarizes the evidence around the use of phytotherapeutics in dental glass-based materials. This review article covers the structure, properties, and clinical uses of GIC and BAG materials within dentistry, with an emphasis on all the attempts that have been made in the last 20 years to enhance their properties naturally using the wisdom of traditional medicines. An extensive electronic search was performed across four databases to include published articles in the last 20 years and the search was concerned only with the English language publications. Publications that involved the use of plant extracts, and their active compounds for the green synthesis of nanoparticles and the modification of GIC and BAG were included up to May 2023. Plant extracts are a potential and effective candidate for modification of different properties of GIC and BAG, particularly their antimicrobial activities. Moreover, natural plant extracts have shown to be very effective in the green synthesis of metal ion nanoparticles in an ecological, and easy way with the additional advantage of a synergistic effect between metal ions and the phytotherapeutic agents. Medicinal plants are considered an abundant, cheap source of biologically active compounds and many of these phytotherapeutics have been the base for the development of new lead pharmaceuticals. Further research is required to assess the safety and the importance of regulation of phytotherapeutics to expand their use in medicine. Graphical Abstract

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Biomechanical behavior of functionally graded S53P4 bioglass-zirconia dental implants: Experimental and finite element analyses

Fabris

Fredel

Souza

et al. 2021

Journal of the Mechanical Behavior of Biomedical Materials

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Erratum: Antibacterial Bioactive Glass, S53P4, for Chronic Bone Infections – A Multinational Study

Cited by 7 publications

References 0 publications

Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review

Recent Evidence on Bioactive Glass Antimicrobial and Antibiofilm Activity: A Mini-Review

Herbalism and glass-based materials in dentistry: review of the current state of the art

Biomechanical behavior of functionally graded S53P4 bioglass-zirconia dental implants: Experimental and finite element analyses

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