Palladium
nanoparticles on the polyaniline (Pd@PANI) catalyst are
now easily prepared on a gram scale through the oxidative polymerization
of aniline in the presence of PdCl2 by using air as a clean
oxidant. The material is found to be very stable and can be stored
for more than one year without deactivation. Thus, it may become a
commercial reagent in organic synthesis, depending on its application
scopes. This article reported the first example of Pd@PANI-catalyzed
Sonogashira couplings free of copper and ligands.