Erratum: Natural killer cells and pregnancy

Abstract

Nature Reviews Immunology 2, 656-663 (2002) On page 657 of this article, three items in the figure in Box 1 are labelled incorrectly: • the adaptor protein of NKG2D binding to MICA/B is labelled 'DAP12'. The correct label is 'DAP10'; • the adaptor protein of NKp30 is labelled 'CB33'. The correct label is 'CD3z'; • the adaptor protein of NKp46 is labelled 'FcRg/CD33'. The correct label is 'FcRg/CD3z'.

Natural Killer Cell Development and Maturation Revisited: Possible Implications of a Novel Distinct Lin−CD34+DNAM-1brightCXCR4+ Cell Progenitor

“…CD9, galectin, alpha-1 integrin, and other adhesion molecules are over-expressed in dNK (57), express major activating NK receptors, including NKp46, NKp30, NKG2D, and DNAM-1, and contain high levels of perforin and granzymes (comparable to CD56 dim peripheral NK cells), but have a poor ability to kill classical NK target cells (22, 58–60). dNK cells are able to release high amounts of cytokines and chemokines (including IL-8, VEGF, SDF-1, and IP-10), which are involved in tissue remodeling, trophoblast migration, and/or neo-angiogenesis and placentation.…”

Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and Mice

“…CD56 superbright uterine natural killer (uNK) cells are present in human endometrium prior to the initiation of pregnancy, and markedly expand and become progressively more granulated during the progesterone-dominated secretory phase after ovulation and throughout the first trimester (1–3). uNK cells within the decidua have a distinct phenotype compared to peripheral blood NK (pbNK) cells and share features of both CD56 bright and CD56 dim pbNK subsets (Table 1).…”

Smoking during pregnancy influences the maternal immune response in mice and humans

“…20 Important players in the adaptation of the maternal immune response are T cells (especially regulatory T cells), natural killer (NK) cells, and monocytes and macrophages. 13,[21][22][23][24] Regulatory T (Treg) cells are a subpopulation of T cells that regulate immune responses. They are important in the process of tolerance to self and foreign antigens, andthey therefore play a role in autoimmune diseases, inflammatory diseases, transplantation, and pregnancy.…”