Erratum to ‘Dead-end and crossflow ultrafiltration process modelling: Application on chemical mechanical polishing wastewaters’ [Chem. Eng. Res. Des. 158 (2020) 164–176]

Ohanessian, Kelly; Monnot, Mathias; Moulin, Philippe; Ferrasse, Jean‐Henry; Barca, Cristian; Soric, Audrey; Boutin, Olivier

doi:10.1016/j.cherd.2020.07.027

Cited by 1 publication

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“…Although an excellent filter is required to ensure a high recovery rate, the filtration method is also important. In general, dead end filtration (DEF) is a unidirectional filtration method that easily blocks filters, whereas tangential flow filtration (TFF) prevents blocking and increases filtration continuity [ 22 ]. However, even during DEF, the recovery rate can be increased by backflushing [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Precise Filtration of Chronic Myeloid Leukemia Cells by an Ultrathin Microporous Membrane with Backflushing to Minimize Fouling

Lee,

Hong,

Lee

et al. 2023

Membranes

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A cell filtration platform that affords accurate size separation and minimizes fouling was developed. The platform features an ultra-thin porous membrane (UTM) filter, a pumping head filtration with backflush (PHF), and cell size measurement (CSM) software. The UTM chip is an ultrathin free-standing membrane with a large window area of 0.68 mm2, a pore diameter of 5 to 9 μm, and a thickness of less than 0.9 μm. The PHF prevents filter fouling. The CSM software analyzes the size distributions of the supernatants and subnatants of isolated cells and presents the data visually. The D99 particle size of cells of the chronic myeloid leukemia (CML) line K562 decreased from 22.2 to 17.5 μm after passage through a 5-μm filter. K562 cells could be separated by careful selection of the pore size; the recovery rate attained 91.3%. The method was compared to conventional blocking models by evaluating the mean square errors (MSEs) between the measured and calculated filtering volumes. The filtering rate was fitted by a linear regression model with a significance that exceeded 0.99 based on the R2 value. The platform can be used to separate various soft biomaterials and afford excellent stability during filtration.

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Section: Introductionmentioning

confidence: 99%