Erratum to “Epidemiological and Clinical-Pathological Aspects of <i>Helicobacter pylori</i> Infection in Brazilian Children and Adults”

Toscano, E.; Madeira, Fernanda Fernandez; Dutra-Rulli, Mayra Pinheiro; Gonçalves, Luiz Otavio Maia; Proença, Marcela Alcântara; Borghi, Viviane Silva; Cadamuro, Aline Cristina Targa; Mazzale, Giselda Warick; Acayaba, Ricardo; Silva, Ana Elizabete

doi:10.1155/2019/5632935

Cited by 3 publications

(5 citation statements)

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“…The high rate of H. pylori acquisition in older children and adults might be explained by their outdoor activities and exposure to potential external sources. These findings are in agreement with those of other studies, which showed that H. pylori infections progressively increase with age [39][40][41][42]. In terms of occupation, surprisingly, it was found that employed participants were found to be infected with H. pylori more often than unemployed participants (p < 0.035).…”

Section: Discussionsupporting

confidence: 93%

Helicobacter pylori Infection in Tripoli, North Lebanon: Assessment and Risk Factors

Khoder

Mina

Mahmoud

et al. 2021

Biology

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Helicobacter pylori (H. pylori) infection occurs among half of the general population worldwide, with high geographic variability. Even though H. pylori is the leading cause of several gastric diseases, ranging from gastritis and peptic ulcers to gastric malignancies, such as gastric cancer and mucosa-associated lymphoid tissue lymphoma, most of the infections remain asymptomatic. Early detection and eradication of H. pylori can definitely prevent severe long-term gastric diseases associated with H. pylori. In Lebanon, the prevalence of H. pylori is not well documented, especially in healthy subjects. The aim of this study is to assess H. pylori infections and the associated risk factors in Tripoli, North Lebanon. A cross-sectional study was conducted on 300 healthy Lebanese volunteers, including both children and adults. The H. pylori stool antigens were detected using the Premier Platinum HpSA test. The socio-demographic data, lifestyle characteristics, and gastrointestinal characteristics of all participants were analyzed. Out of the 300 tested volunteer subjects, 31% were found to be positive for H. pylori. A multivariate binary logistic regression analysis for factors associated with H. pylori infection revealed a significant association between H. pylori infection and gastrointestinal disturbances, the crowding index, and occupation. A significant statistical correlation was found between sheesha smoking (p = 0.001) and H. pylori infection. These findings highlight the need for the development of preventive approaches and strategic indications for the appropriate treatment of H. pylori infections in Tripoli, North Lebanon.

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Section: Discussionsupporting

confidence: 93%

Helicobacter pylori Infection in Tripoli, North Lebanon: Assessment and Risk Factors

Khoder

Mina

Mahmoud

et al. 2021

Biology

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“…According to the results of gold test, the H. pylori infection identified in 31% of our study group was higher comparing with that reported by authors in other context. In pediatric and adolescent Brazilian population (29), in a group of Saudi Arabian school students (30), in Iran (31), in Sudan (32) and in Jordan (33) the frequency of H. pylori infection was respectively, 24.7%, 27.4%, 19.8%, 8% and 14.6%. In Moroccan adult group, H. pylori was detected in 87 (57.24%), and 69 (45.10%) cases by histology, and PCR, respectively (34), in 75.5% among 324 patients (35) and in 69.9% of 429 patients (36).…”

Section: Discussionmentioning

confidence: 98%

The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

Hibaoui¹,

Massik²,

Lebbar³

et al. 2022

IJM

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Background and Objectives: Infesting nearly 50% of the world's population, Helicobacter pylori are thought to cause pep- tic ulcers, as well as gastricadenocarcinoma. Several diagnostic methods are available to detect this bacterium; however, at least two must be used together for an accurate diagnosis. Thisstudy evaluated the use of rapid urease test for diagnosis of H. pylori infection in a pediatric population. Materials and Methods: Five gastric biopsies were taken from children during a 2-year period for the purpose of histolog- ical, molecular, bacteriological culture, and rapid urease testing. Results: Among 83 children, 38 were male, and 45 were female with an age ranging of 2 to 15 years. The infected group represented 31%. The rapid ureasetest had a sensitivity of 88.5%, a negative predictive value of 94%, a specificity of 84.2%, and a positive predictive value of 72%. Conclusion: A rapid urease test may be appropriate for ruling out H. pylori infection after a negative result. The positive results however, may be confirmed by a second invasive test.

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“…Alternatively, it may be a case of selection biases where patients seeing doctor regularly get tested for H. pylori more often than those patients seeing doctors for a cause [38]. There are various potential sources of bias and confounding variables, including the fact that individuals with Crohn's disease may have received other medical treatments that have an effect on H. pylori, or the fact that publishing biases may have distorted the findings [35,39].…”

Section: Epidemiological Correlation Between CD and H Pylorimentioning

confidence: 99%

“…Various researches included the ecological epidemiology studies in order to tackle the issue of overcoming biases and confounding in their researches. Information regarding the prevalence and incidence of CD was combined with geographically and temporally matched studies of the prevalence of H. pylori [2,3,16,17,30,39]. Shah et al also expanded that epidemiology study strategy and conduct an in-depth analysis of the published researches on the epidemiology of Crohn's disease from 1990 to 2016, comparing the findings of this research with findings on the incidence of H. pylori infection.…”

Section: Epidemiological Correlation Between CD and H Pylorimentioning

confidence: 99%

“…There have been conflicting reports on using probiotics in terms of efficacy as part of a therapeutic strategy to eradicate H. pylori. In a number of clinical studies, the standard triple therapy for H. pylori was supplemented with adjuvant medications (such as lactoferrin and probiotics), trying to lower the risks of adverse side effects and raising the change of complete eradication [9,35,39,50,54]. The addition of lactoferrin or probiotics to the triple therapy did not result in an increase in the rate of H. pylori eradication; however, it did result in a reduction in epigastric pain, vomiting, and diarrhea, indicating a less degree of inflammation [53,57].…”

Section: Molecular Mechanismsmentioning

confidence: 99%

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Helicobacter Pylori Infection Correlates with Lower Prevalence and Subsequent Incidence of Crohn’s Disease

Hu¹,

Lei²,

Tai³

et al. 2024

Helicobacter Pylori Infection - An Up to Date on the Pathogenic Mechanisms, Diagnosis and Clinical Management

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According to some researchs, Crohn’s disease (CD) and Ulcerative colitis (UC), two chronic inflammatory bowel illnesses, may be protected against Helicobacter pylori infection. Many case–control studies have revealed that individuals with CD and UC had lower H. pylori prevalence than healthy controls. However, whether or not H. pylori plays a protective role in the development of Crohn’s disease is debatable. CD was more common in H. pylori-negative individuals than in H. pylori-positive patients. After eradication of H. pylori, the CD was more common in the H. pylori-negative group than in the H. pylori-positive group over the previous research follow-up period. Although it has been strongly indicated in previous studies that H. pylori infection plays a significant role and triggers autoimmune reactions and may be implicated in the pathogenesis of autoimmune diseases, the role of H. pylori in inflammatory bowel disease, including Crohn’s disease, is unclear.

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Erratum to “Epidemiological and Clinical-Pathological Aspects of Helicobacter pylori Infection in Brazilian Children and Adults”

Cited by 3 publications

References 1 publication

Helicobacter pylori Infection in Tripoli, North Lebanon: Assessment and Risk Factors

Helicobacter pylori Infection in Tripoli, North Lebanon: Assessment and Risk Factors

The high sensitivity and specificity of rapid urease test in diagnosis of Helicobacter pylori infection in Moroccan children

Helicobacter Pylori Infection Correlates with Lower Prevalence and Subsequent Incidence of Crohn’s Disease

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