Erratum to ‘pH-sensitive sodium alginate hydrogels for riboflavin controlled release’ [Carbohydr. Polym. 89 (2) (2012) 667–675]

El‐Ghaffar, M. A. Abd; Hashem, M.S.; Awady, Mostafa K El; Rabie, Ahmed

doi:10.1016/j.carbpol.2012.05.045

Cited by 22 publications

(33 citation statements)

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“…pH 4.5, particularly in the absence of a strong buffer . Notably, alginate hydrogels, at least in some compositions, demonstrate pH sensitivity and swelling at acidic pH values . Therefore, one has to verify which mechanism, pH change or H 2 O 2 formation, is responsible for insulin release in our system.…”

Section: Resultsmentioning

confidence: 99%

Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

et al. 2017

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We study the mechanisms involved in the release, triggered by the application of glucose, of insulin entrapped in Fe -cross-linked alginate hydrogel particles further stabilized with a polyelectrolyte. Platelet-shaped alginate particles are synthesized containing enzyme glucose oxidase conjugated with silica nanoparticles, which are also entrapped in the hydrogel. Glucose diffuses in from solution, and production of hydrogen peroxide is catalyzed by the enzyme within the hydrogel. We argue that, specifically for the Fe -cross-linked systems, the produced hydrogen peroxide is further converted to free radicals via a Fenton-type reaction catalyzed by the iron cations. The activity of free radicals, as well as the reduction of Fe by the enzyme, and other mechanisms contribute to the decrease in density of the hydrogel. As a result, while the particles remain intact, void sizes increase and release of insulin ensues and is followed experimentally. A theoretical description of the involved processes is proposed and utilized to fit the data. It is then used to study the long-time properties of the release process that offers a model for designing new drug-release systems.

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Section: Resultsmentioning

confidence: 99%

Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

et al. 2017

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“…Alginate is a common and typical biomaterial that has been extensively studied on account of its high biocompatibility, low toxicity, relatively low cost, and the safe mild gelation condition with divalent cations such as Ca 2+ and Ba 2+ , which are preferred as candidates for biomedical applications, for instance, drug delivery, tissue scaffold, wound dressing, and so on. Alginate is a polysaccharide naturally found in all species of brown algae and some bacteria, which is a common term used for a family of polyanionic linear polymers composed of 1,4‐linked β‐D‐mannuronic and α‐L‐guluronic acid residues in varying proportions, sequence, and molecular weight …”

Section: Introductionmentioning

confidence: 99%

Influence of K⁺ and Na⁺ ions on the degradation of wet‐spun alginate fibers for tissue engineering

Zhang

Huang

Jin

2016

J of Applied Polymer Sci

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A synthetic type of wet‐spun alginate fibers were immersed in simulated body fluid(SBF) composed of K+, Na+, and Ca2+ cations with various concentrations. Experimental measurements revealed that Na+ had a greater impact on degradability than that of K+ ion. The finding was further confirmed by the characterization of mass loss, ICP, XRD, and theoretical analyses. The degradation process and mechanism were demonstrated through the research on swelling behavior and mass loss. Besides, the wet‐spun alginate fibers were characterized by FT‐IR, XRD, and SEM. The results showed that the degradation mechanism could be attributed to the ion‐exchange between Ca2+ of the synthetic alginate fibers and Na+, K+ of the solutions under the osmotic pressure. The synthetic fibers were swelled and then degraded faster with the presence of Na+ ion presented greater influence on degradability compared with K+ ion. The degradation results of a mechanical rupture of fibers due to excessive water uptake without the occurrence of any chemical changes in the spun alginates structure. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44396.

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“…SD‐pH curves are shown in Figure . SDs of all samples are low when pH ≤ 3 because most of the – COO – groups of CaA are transformed into – COOH . Intermolecular hydrogen bonds are formed between the carboxylate groups of CaA and predominate over the polymer – H 2 O interactions.…”

Section: Resultsmentioning

confidence: 99%

BSA imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres

Liu

Ying

Wang

et al. 2016

J of Applied Polymer Sci

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Polyethylene glycol grafted calcium alginate hydrogel microspheres are synthesized by ring‐opening and addition reaction of epoxy chloropropane. FTIR, 13C NMR, optical microscope, SEM, TG, and DSC are used for characterization. Swelling behaviors are studied and it is found that polyethylene glycol grafted calcium alginate microspheres are improved in anti‐swelling properties. Protein‐imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres exhibit enhanced specific rebinding quantity (11.16 mg/g) and selective recognition properties (4.71 against BHb), towards target molecule in the presence of competing protein, compared with that of the unmodified samples (4.96 mg/g and 1.75, respectively). © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43617.

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Erratum to ‘pH-sensitive sodium alginate hydrogels for riboflavin controlled release’ [Carbohydr. Polym. 89 (2) (2012) 667–675]

Cited by 22 publications

References 0 publications

Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Influence of K⁺ and Na⁺ ions on the degradation of wet‐spun alginate fibers for tissue engineering

BSA imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres

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Erratum to ‘pH-sensitive sodium alginate hydrogels for riboflavin controlled release’ [Carbohydr. Polym. 89 (2) (2012) 667–675]

Cited by 22 publications

References 0 publications

Glucose‐Triggered Insulin Release from Fe3+‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Glucose‐Triggered Insulin Release from Fe3+‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Influence of K+ and Na+ ions on the degradation of wet‐spun alginate fibers for tissue engineering

BSA imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres

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Product

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Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Glucose‐Triggered Insulin Release from Fe³⁺‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

Influence of K⁺ and Na⁺ ions on the degradation of wet‐spun alginate fibers for tissue engineering