Erratum to “Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cγ and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages” [Neurobiol. Dis. 15 (2004) 279–286]

Expression of the Ets transcription factor Erm is regulated through a conventional PKC signaling pathway in the Molt4 lymphoblastic cell line

“…In order to confirm the involvement of the cPKC sub‐family in erm expression, we also tested the BAPTA/AM, which is an intracellular Ca 2+ chelator. In fact, only the cPKCs require Ca 2+ [15]. We showed that erm mRNA upregulation depends on intracellular Ca 2+ accessibilities, since BAPTA/AM can reverse PMA‐induced erm expression in Molt4 cells (Fig.…”

“…Since the phorbol ester PMA acts through the PKC pathway [18,19], and using specific inhibitors such as emodin and H89, we were able to exclude the involvement of the CK2 and PKA pathways, respectively, in the PMA‐induced erm expression in Molt4 cells. The data obtained on erm expression, with either the specific intracellular Ca 2+ chelator BAPTA/AM [15] or the specific PKC activators Bryostatin 1 and Thymeleatoxin [14], permit us to more precisely determine which of the 11 PKCs are involved in this process, i.e., the α, β1 and γ isoforms.…”