Error in Principles and Practice of Infectious Diseases

Mandell, Gerald L.; Douglas, R. Gordon; Bennett, John E.

doi:10.7326/0003-4819-92-6-875_1

Cited by 178 publications

(293 citation statements)

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“…Although contamination of bandages with Absidia spp. has been noted, 2 no outbreak has been associated with this. There have been some reports of sporadic cases of cutaneous mucormycosis related to predisposing skin lesions and contact with contaminated material, such as adhesive bandages and tongue depressors placed close to intravenous catheter insertion sites.…”

mentioning

confidence: 85%

An outbreak of Absidia corymbifera infection associated with bandage contamination in a burns unit

Christiaens

Hayette

Jacquemin

et al. 2005

Journal of Hospital Infection

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mentioning

confidence: 85%

An outbreak of Absidia corymbifera infection associated with bandage contamination in a burns unit

Christiaens

Hayette

Jacquemin

et al. 2005

Journal of Hospital Infection

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“…The patient's condition and the results of laboratory and colonoscopic examinations deteriorated further in spite of administration of the recommended oral vancomycin dosage of 125 mg four times a day, which should result in an approximate 300-1000 mg/l stool concentration. 9 To our knowledge, no such resistance to vancomycin has been previously documented in the literature. Robert et al 27 have described the in vivo resistance of C. difficile to tetracycline, clindamycin, and in vitro resistance of C. difficile to vancomycin.…”

Section: Discussionmentioning

confidence: 82%

“…In neutropenic patients local invasion of the intestinal mucosa by C. difficile has also been observed. 9 Successful therapy depends on early clinical and microbiological diagnosis confirmed by colonoscopy. Laboratory examinations include microscopy, anaerobic stool culture and toxin A detection by immunoassay; sometimes latexagglutination is used.…”

mentioning

confidence: 99%

Pseudomembraneous clostridium after autologous bone marrow transplantation

Kavan

Sochor

Nyč

et al. 1998

Bone Marrow Transplant

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Summary:Clostridium difficile (C. difficile) pseudomembraneous colitis was diagnosed in a 13-year-old boy with Hodgkin's disease 3 months after autologous bone marrow transplantation. Hematopoiesis was fully reconstituted at the time. C. difficile infection occurred after gall bladder empyema had been treated conservatively with i.v. antibiotics and prophylactic 4-week administration of oral amoxicillin. C. difficile colitis was diagnosed early and intensive supportive therapy combined with administration of i.v. and subsequently oral vancomycin therapy failed. It is a phenomenon rarely seen and successful eradication of the clostridium infection was only achieved by a combination of higher dose vancomycin with metronidazole. During the post-colitis recovery the patient experienced a relapse of Hodgkin's disease and died following further surgical intervention 137 days post-transplantation.

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“…Both of these staphylococci have been shown to cause an array of ophthalmological pathology including conjunctivitis and endophthalmitis. 2 It is likely that the Bacillus species and micrococcus are air contaminants and are not potential sources of pathological infection. A healthy tear film covering an intact healthy eye provides good protection against bacteria.…”

Section: Discussionmentioning

confidence: 99%

Contamination of disposable tonometer prisms during tonometry

Rajak

Paul

Sharma

et al. 2005

Eye

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Aim Due to the theoretical possibility of prion transmission in applanation tonometry, many ophthalmological units in the United Kingdom now use disposable tonometer prisms. We have investigated the potential for bacterial and viral transmission from the health practitioner to the patient via disposable prisms. Methods All staff who perform applanation tonometry at the Sussex Eye Hospital (SEH) received a questionnaire to evaluate if the applanating face of the prism is touched during tonometry and the ease of use of the disposable prism compared to the reusable prisms that were previously used. We then cultured prisms handled by a random sample of staff members for common bacteria. Finally, we constructed a model to investigate the possibility of interpatient adenoviral transmission via disposable tonometer prisms. Results The questionnaire revealed that almost 50% of the staff admit to touching the applanating face of the tonometer prism prior to applanation. Cultures of the prisms grew a range of bacteria including Staphylococcus epidermidis, Staphylococcus aureus, and Bacillus species. The viral model suggested that adenovirus could be transmitted by applanation tonometry. Conclusion The use of disposable prisms for applanation tonometry may reduce the risk of prion transmission but is not bacteriologically or virologically aseptic. This is a potential infection risk to patients.

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Error in Principles and Practice of Infectious Diseases

Cited by 178 publications

References 0 publications

An outbreak of Absidia corymbifera infection associated with bandage contamination in a burns unit

An outbreak of Absidia corymbifera infection associated with bandage contamination in a burns unit

Pseudomembraneous clostridium after autologous bone marrow transplantation

Contamination of disposable tonometer prisms during tonometry

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